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Anhedonia reduction correlates with increased ventral caudate connectivity with superior frontal gyrus in depression
Yang, Xinhua1,2; Huang, Jia3,4; Roser, Matthew E.2; Xie, Guangrong5
通讯作者Yang, Xinhua(xinhua.yang@kcl.ac.uk)
摘要This study was to investigate the relationship between the ventral caudate connectivity and anhedonia. Nineteen depressed patients and 16 healthy controls participated in two identical functional magnetic resonance imaging scans during a 1-year period to determine the resting-state functional connectivity changes using a seed-based approach. Patients showed increased left ventral caudate functional connectivity with superior frontal gyrus over time and the increased connectivity was associated with anhedonia improvement. None of these associations were observed in healthy controls. The findings suggest that left ventral caudate may serve as a potential target to improve the severity of anhedonia.
关键词Anhedonia Ventral caudate Superior frontal gyrus
2022-07-01
语种英语
DOI10.1016/j.jpsychires.2022.04.030
发表期刊JOURNAL OF PSYCHIATRIC RESEARCH
ISSN0022-3956
卷号151页码:286-290
收录类别SCI
资助项目Natural Science Foundation of Hunan Province[2019JJ40118] ; CAS Key Laboratory of Mental Health of the Institute of Psychology
出版者PERGAMON-ELSEVIER SCIENCE LTD
WOS关键词FUNCTIONAL CONNECTIVITY ; STRIATAL CONNECTIVITY ; MAJOR DEPRESSION ; TEMPORAL GYRUS
WOS研究方向Psychiatry
WOS类目Psychiatry
WOS记录号WOS:000806169400011
资助机构Natural Science Foundation of Hunan Province ; CAS Key Laboratory of Mental Health of the Institute of Psychology
引用统计
文献类型期刊论文
条目标识符http://ir.psych.ac.cn/handle/311026/42929
通讯作者Yang, Xinhua
作者单位1.Shanghai Changning Mental Hlth Ctr, 299 Xiehe Rd, Shanghai 200335, Peoples R China
2.Plymouth Univ, Fac Hlth & Human Sci, Brain Res & Imaging Ctr, Cognit Inst,Sch Psychol, Plymouth, Devon, England
3.Chinese Acad Sci, Inst Psychol, Neuropsychol & Appl Cognit Neurosci Lab, CAS Key Lab Mental Hlth, Beijing, Peoples R China
4.Univ Chinese Acad Sci, Dept Psychol, Beijing, Peoples R China
5.Cent South Univ, Mental Hlth Inst, Natl Technol Inst Psychiat, Key Lab Psychiat & Mental Hlth Hunan Prov,Xiangya, Changsha, Hunan, Peoples R China
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GB/T 7714
Yang, Xinhua,Huang, Jia,Roser, Matthew E.,et al. Anhedonia reduction correlates with increased ventral caudate connectivity with superior frontal gyrus in depression[J]. JOURNAL OF PSYCHIATRIC RESEARCH,2022,151:286-290.
APA Yang, Xinhua,Huang, Jia,Roser, Matthew E.,&Xie, Guangrong.(2022).Anhedonia reduction correlates with increased ventral caudate connectivity with superior frontal gyrus in depression.JOURNAL OF PSYCHIATRIC RESEARCH,151,286-290.
MLA Yang, Xinhua,et al."Anhedonia reduction correlates with increased ventral caudate connectivity with superior frontal gyrus in depression".JOURNAL OF PSYCHIATRIC RESEARCH 151(2022):286-290.
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