Neural Substrates of External and Internal Visual Sensations Induced by Human Intracranial Electrical Stimulation

doi:10.3389/fnins.2022.918767

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	Neural Substrates of External and Internal Visual Sensations Induced by Human Intracranial Electrical Stimulation
	Li, Yanyan 1,2; Tan, Zheng 1,2; Wang, Jing 3; Wang, Mengyang 3; Wang, Liang 1,2
通讯作者	Wang, Mengyang(mengyangwang@ccmu.edu.cn) ; Wang, Liang(lwang@psych.ac.cn)
摘要	Offline perceptions are self-generated sensations that do not involve physical stimulus. These perceptions can be induced by external hallucinated objects or internal imagined objects. However, how the brain dissociates these visual sensations remains unclear. We aimed to map the brain areas involved in internal and external visual sensations induced by intracranial electrical stimulation and further investigate their neural differences. In this study, we collected subjective reports of internal and external visual sensations elicited by electrical stimulation in 40 drug-refractory epilepsy during presurgical evaluation. The response rate was calculated and compared to quantify the dissociated distribution of visual responses. We found that internal and external visual sensations could be elicited when different brain areas were stimulated, although there were more overlapping brain areas. Specifically, stimulation of the hippocampus and inferior temporal cortex primarily induces internal visual sensations. In contrast, stimulation of the occipital visual cortex mainly triggers external visual sensations. Furthermore, compared to that of the dorsal visual areas, the ventral visual areas show more overlap between the two visual sensations. Our findings show that internal and external visual sensations may rely on distinct neural representations of the visual pathway. This study indicated that implantation of electrodes in ventral visual areas should be considered during the evaluation of visual sensation aura epileptic seizures.
关键词	offline perception intracranial electrical stimulation epilepsy hippocampus inferior temporal cortex
	2022-07-22
语种	英语
DOI	10.3389/fnins.2022.918767
发表期刊	FRONTIERS IN NEUROSCIENCE
卷号	16 页码:11
收录类别	SCI
出版者	FRONTIERS MEDIA SA
WOS关键词	INTRACEREBRAL STIMULATION ; HALLUCINATIONS ; PERCEPTION ; NETWORKS ; IMAGERY ; CORTEX ; BRAIN ; SIZE
WOS研究方向	Neurosciences & Neurology
WOS类目	Neurosciences
WOS记录号	WOS:000837075700001
引用统计
文献类型	期刊论文
条目标识符	http://ir.psych.ac.cn/handle/311026/43046
通讯作者	Wang, Mengyang; Wang, Liang
作者单位	1.Inst Psychol, CAS Key Lab Mental Hlth, Beijing, Peoples R China 2.Univ Chinese Acad Sci, Dept Psychol, Beijing, Peoples R China 3.Capital Med Univ, Sanbo Brain Hosp, Beijing, Peoples R China
推荐引用方式 GB/T 7714	Li, Yanyan,Tan, Zheng,Wang, Jing,et al. Neural Substrates of External and Internal Visual Sensations Induced by Human Intracranial Electrical Stimulation[J]. FRONTIERS IN NEUROSCIENCE,2022,16:11.
APA	Li, Yanyan,Tan, Zheng,Wang, Jing,Wang, Mengyang,&Wang, Liang.(2022).Neural Substrates of External and Internal Visual Sensations Induced by Human Intracranial Electrical Stimulation.FRONTIERS IN NEUROSCIENCE,16,11.
MLA	Li, Yanyan,et al."Neural Substrates of External and Internal Visual Sensations Induced by Human Intracranial Electrical Stimulation".FRONTIERS IN NEUROSCIENCE 16(2022):11.