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阻碍条件性恐惧记忆消退的原因分析
Alternative TitleReasons Block Extinction of Conditioned Fear Memory
安献丽; 王文忠; 郑希耕
2009
Source Publication心理科学进展
ISSN1671-3710
Volume17Issue:1Pages:126-131
Abstract创伤后应激障碍是个体经历严重应激后形成的一种焦虑障碍,对其治疗的关键是消退由创伤应激导致的条件性恐惧记忆,但目前最有效的暴露疗法并不能真正有效地抑制患者恐惧记忆的表达。对条件性恐惧的动物模型研究发现情绪性增强效应、恐惧记忆二级条件化与再巩固、内侧前额叶皮层功能不足等均能够阻碍条件性恐惧记忆的消退。针对这几个方面可以探索治疗创伤后应激障碍的相应方法。
Keyword条件性恐惧记忆 消退 情绪性增强效应 二级条件化 再巩固 内侧前额叶皮层
Subject Area认知神经科学
Language中文
Funding Project国家自然科学基金(30470578,30770722,30840001);;中国科学院心理研究所科学发展基金资助
NotePosttraumatic stress disorder is a kind of anxiety disorder which developed after severe trauma. The key of treatment for this disorder is to extinct the conditioned fear memory acquired in trauma. But the most effective exposure therapy can’t repress fear memory efficiently. Researches from animal model of fear conditioning showed that: enhancing effects of emotional arousal, secondary-order conditioning and reconsolidation of fear memory, deficient function of medial prefrontal cortex etc all are reasons block the extinction of fear memory. According to these reasons,corresponding treatment ways can be explored and developed.
Document Type期刊论文
Identifierhttp://ir.psych.ac.cn/handle/311026/4354
Collection中国科学院心理研究所回溯数据库(1956-2010)
Corresponding Author郑希耕
Recommended Citation
GB/T 7714
安献丽,王文忠,郑希耕. 阻碍条件性恐惧记忆消退的原因分析[J]. 心理科学进展,2009,17(1):126-131.
APA 安献丽,王文忠,&郑希耕.(2009).阻碍条件性恐惧记忆消退的原因分析.心理科学进展,17(1),126-131.
MLA 安献丽,et al."阻碍条件性恐惧记忆消退的原因分析".心理科学进展 17.1(2009):126-131.
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