Institutional Repository of Key Laboratory of Mental Health, CAS
Insomnia in Chinese patients with chronic schizophrenia: prevalence, clinical correlates and relationship with cognitive impairment | |
Zhu, Rongrong1,2; Zhou, Yongjie3; Wei, Shuochi1,2; Wang, Wenjia1,2; Wang, Dongmei1,2; Wang, Li1,2; Zhang, Xiang-Yang1,2 | |
第一作者 | Rongrong Zhu1 |
通讯作者邮箱 | zhangxy@psych.ac.cn (x. yang zhang). |
心理所单位排序 | 1 |
摘要 | Purpose Insomnia is a major public health concern that often occurs in patients with schizophrenia, complicating the treatment and prognosis of patients. This study aimed to investigate the prevalence of insomnia and its relationship with cognitive function in Chinese patients with chronic schizophrenia. Methods We recruited patients with schizophrenia and collected their clinical and demographic data. Insomnia data were collected through a self-reported questionnaire consisting of three questions. The positive and negative syndrome scale (PANSS) was used to measure psychopathological symptoms, while the repeatable battery for the assessment of neuropsychological status (RBANS) was used to measure cognitive performance. Results Of 957 Chinese patients with chronic schizophrenia 20.2% reported having insomnia (193/957). Male patients (107/630, 17.0%) had a lower rate of insomnia than female patients (86/327, 26.3%) (x(2) = 11.60, p = 0.001). Patients with insomnia exhibited significantly higher PANSS total score and positive symptom, negative symptom, and general psychopathology scores, but significantly lower RBANS total score, language, attention and delayed memory scores compared to patients without insomnia (all p < 0.05). Logistic regression analysis showed that female sex, high PANSS total score and the use of diazepam were independently associated with insomnia (all p < 0.05). Conclusions Insomnia is relatively common in Chinese patients with chronic schizophrenia. Some demographic data and clinical symptoms are associated with insomnia. Patients with schizophrenia and insomnia perform poorly on cognition tests suggesting that insomnia and cognitive function are closely related in patients with schizophrenia. |
关键词 | Schizophrenia Clinical symptom Cognitive performance Insomnia |
2022-12-16 | |
DOI | 10.1007/s11325-022-02762-4 |
发表期刊 | SLEEP AND BREATHING |
ISSN | 1520-9512 |
页码 | 7 |
期刊论文类型 | 实证研究 |
收录类别 | SCI |
资助项目 | Chinese National Programs for Brain Science ; Brain-like Intelligence Technology ; National Natural Science Foundation of China[2021ZD0202102] ; CAS International Cooperation Research Program[31300848] ; CAS International Cooperation Research Program[31800930] ; [153111KYSB20190004] |
出版者 | SPRINGER HEIDELBERG |
WOS关键词 | QUALITY-OF-LIFE ; SLEEP DISTURBANCE ; SYMPTOMS ; BDNF |
WOS研究方向 | Neurosciences & Neurology ; Respiratory System |
WOS类目 | Clinical Neurology ; Respiratory System |
WOS记录号 | WOS:000899532100001 |
资助机构 | Chinese National Programs for Brain Science ; Brain-like Intelligence Technology ; National Natural Science Foundation of China ; CAS International Cooperation Research Program |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.psych.ac.cn/handle/311026/44371 |
专题 | 中国科学院心理健康重点实验室 |
通讯作者 | Zhang, Xiang-Yang |
作者单位 | 1.Chinese Acad Sci, Inst Psychol, CAS Key Lab Mental Hlth, 16 Lincui Rd, Beijing 100101, Peoples R China 2.Univ Chinese Acad Sci, Dept Psychol, Beijing, Peoples R China 3.Shenzhen Kangning Hosp, Dept Psychiat Rehabil, Shenzhen, Peoples R China |
第一作者单位 | 中国科学院心理健康重点实验室 |
通讯作者单位 | 中国科学院心理健康重点实验室 |
推荐引用方式 GB/T 7714 | Zhu, Rongrong,Zhou, Yongjie,Wei, Shuochi,et al. Insomnia in Chinese patients with chronic schizophrenia: prevalence, clinical correlates and relationship with cognitive impairment[J]. SLEEP AND BREATHING,2022:7. |
APA | Zhu, Rongrong.,Zhou, Yongjie.,Wei, Shuochi.,Wang, Wenjia.,Wang, Dongmei.,...&Zhang, Xiang-Yang.(2022).Insomnia in Chinese patients with chronic schizophrenia: prevalence, clinical correlates and relationship with cognitive impairment.SLEEP AND BREATHING,7. |
MLA | Zhu, Rongrong,et al."Insomnia in Chinese patients with chronic schizophrenia: prevalence, clinical correlates and relationship with cognitive impairment".SLEEP AND BREATHING (2022):7. |
条目包含的文件 | ||||||
文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
Insomnia in Chinese (633KB) | 期刊论文 | 出版稿 | 限制开放 | CC BY-NC-SA | 请求全文 |
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