Evaluation of Electroconvulsive Therapy in Adolescents With Major Depressive and Bipolar Disorders A Retrospective Analysis

doi:10.1097/YCT.0000000000000894

	Evaluation of Electroconvulsive Therapy in Adolescents With Major Depressive and Bipolar Disorders A Retrospective Analysis
	Shao, Wen 1; Zheng, Yi 2; Li, Qingxia 3; Shao, Kangning 1,4; Zhao, Fujun 5; Guan, Lin 2; Zhang, Zhixia 2; Li, Fenghua1
通讯作者	Li, Fenghua(lifh@psych.ac.cn)
摘要	ObjectiveThis study aims to provide an evaluation of electroconvulsive therapy (ECT) in hospitalized adolescents with major depressive and bipolar disorders by examining its treatment outcomes as well as comparing it with outcomes of hospitalized patients, treated as usual (TAU).MethodsThis is a retrospective study based on medical records documented between April 2011 and December 2017 from Beijing An Ding Hospital. Patients were diagnosed according to the International Classification of Diseases, Tenth Revision. The study included 288 inpatients, with 2 groups of 171 patients treated by ECT and 117 TAU. The primary outcome was measured using the severity subscale of Clinical Global Impression. Mann-Whitney U test, chi(2) test, and linear regression with mixed models were used to analyze the data.ResultsSymptom severity reduced significantly for both groups (beta = -0.62, t(975.93) = -20.54, P < 0.001). The TAU group was associated with lower score on the severity subscale of Clinical Global Impression (beta = 0.28, t(980.32) = 8.36, P < 0.001). The ECT group had a higher remission rate (28.65%) than the TAU group (16.24%), but the time required for remission was longer (U [N-ECT = 49, N-TAU = 19] = 615, z = 2.10, P = 0.04). Adverse events of ECT were barely observed.ConclusionElectroconvulsive therapy is an efficacious and safe treatment for adolescents. However, as the superiority in efficacy was not evident in ECT group, its prescription should be prudently considered for younger patients who respond well to other treatments.
关键词	adolescents ECT mood disorder safety treatment outcome
	2023-06-01
语种	英语
DOI	10.1097/YCT.0000000000000894
发表期刊	JOURNAL OF ECT
ISSN	1095-0680
卷号	39 期号:2 页码:111-116
收录类别	SCI
出版者	LIPPINCOTT WILLIAMS & WILKINS
WOS关键词	RATING-SCALE ; VALIDITY ; ANXIETY ; SPEED ; MANIA
WOS研究方向	Behavioral Sciences ; Psychiatry
WOS类目	Behavioral Sciences ; Psychiatry
WOS记录号	WOS:000995034200013
引用统计	被引频次：1[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.psych.ac.cn/handle/311026/45450
专题	中国科学院心理健康重点实验室
通讯作者	Li, Fenghua
作者单位	1.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing, Peoples R China 2.Capital Med Univ, Beijing Ding Hosp, Beijing, Peoples R China 3.South China Normal Univ, Sch Psychol, Guangzhou, Guangdong, Peoples R China 4.Zhengzhou Univ, Affiliated Hosp 2, Zhengzhou, Peoples R China 5.Capital Med Univ, Beijing Childrens Hosp, Natl Ctr Childrens Hlth, Beijing, Peoples R China
第一作者单位	中国科学院心理健康重点实验室
通讯作者单位	中国科学院心理健康重点实验室
推荐引用方式 GB/T 7714	Shao, Wen,Zheng, Yi,Li, Qingxia,et al. Evaluation of Electroconvulsive Therapy in Adolescents With Major Depressive and Bipolar Disorders A Retrospective Analysis[J]. JOURNAL OF ECT,2023,39(2):111-116.
APA	Shao, Wen.,Zheng, Yi.,Li, Qingxia.,Shao, Kangning.,Zhao, Fujun.,...&Li, Fenghua.(2023).Evaluation of Electroconvulsive Therapy in Adolescents With Major Depressive and Bipolar Disorders A Retrospective Analysis.JOURNAL OF ECT,39(2),111-116.
MLA	Shao, Wen,et al."Evaluation of Electroconvulsive Therapy in Adolescents With Major Depressive and Bipolar Disorders A Retrospective Analysis".JOURNAL OF ECT 39.2(2023):111-116.