Overweight or Obesity among Chinese Han People with Schizophrenia: Demographic, Clinical and Cognitive Correlations

doi:10.3390/brainsci13091245

PSYCH OpenIR

	Overweight or Obesity among Chinese Han People with Schizophrenia: Demographic, Clinical and Cognitive Correlations
	Huang, Xiao 1; Sun, Yuan 2; Wu, Anshi 1; Zhang, Xiangyang 3,4
通讯作者	Zhang, Xiangyang(zhangxy@psych.ac.cn)
摘要	People with schizophrenia are more likely to be afflicted by obesity or overweight compared to the general population. This study aimed to explore the incidence of overweight and obesity, clinical features and cognitive performance of Chinese Han patients with chronic schizophrenia who had overweight or obesity. We obtained data from 985 schizophrenia inpatients about overweight and obesity through body mass index (BMI). All patients were evaluated with the positive and negative syndrome scale, the Mini-mental State Examination (MMSE) and the repeated battery for evaluation of the neuropsychological status (RBANS) scale. We collected demographic and clinical data using self-reported questionnaires. We divided patients into normal weight (BMI < 24 kg/m(2)), overweight (24 <= BMI < 28 kg/m(2)) and obese (>= 28 kg/m(2)) groups according to the Working Group on Obesity in China (WGOC) criteria. We compared the clinical data between the three groups and then conducted binary logistic regression and linear regression to assess variables that were significantly associated with overweight and obesity and higher BMI. Of the sample, 324 (32.9%) and 191 (19.4%) patients had overweight and obesity, respectively. Patients who had overweight and obesity were younger, had less education, had higher waist and hip circumferences, higher rates of diabetes and a higher sumPANSP score (compared with patients in the normal group, p < 0.05). There were more female patients with obesity (compared with patients in the normal and overweight groups, p < 0.05). Logistic regression analysis indicated that overweight and obesity were associated with sumPANSP (OR = 1.03, 95%CI = 1-1.061, p = 0.049) and diabetes (OR = 1.891, 95%CI = 1.255-2.849, p = 0.002). Further linear regression showed that age (B = -0.004, t = -2.83, p = 0.005), educational level (B = -0.037, t = -2.261, p = 0.024), diabetes (B = 0.133, t = 2.721, p = 0.007) and sumPANSP (B = 0.008, t = 2.552, p = 0.011) were risk factors for higher BMI. We did not find cognitive performance differences between patients with or without overweight and obesity. Overweight and obesity were associated with some demographic and clinical factors in patients with persistent schizophrenia.
关键词	schizophrenia Chinese Han demographics overweight obesity cognition
	2023-09-01
语种	英语
DOI	10.3390/brainsci13091245
发表期刊	BRAIN SCIENCES
卷号	13 期号:9 页码:11
收录类别	SCI
资助项目	We thank all clinical psychiatrists, nurses, and patients who participated in the study.
出版者	MDPI
WOS关键词	PANSS ; RISK
WOS研究方向	Neurosciences & Neurology
WOS类目	Neurosciences
WOS记录号	WOS:001076942500001
资助机构	We thank all clinical psychiatrists, nurses, and patients who participated in the study.
引用统计
文献类型	期刊论文
条目标识符	http://ir.psych.ac.cn/handle/311026/46136
通讯作者	Zhang, Xiangyang
作者单位	1.Capital Med Univ, Beijing Chao Yang Hosp, Dept Anesthesiol, Beijing 100020, Peoples R China 2.Peking Univ Third Hosp, Dept Pharm, Beijing 100191, Peoples R China 3.Inst Psychol, CAS Key Lab Mental Hlth, Beijing 100101, Peoples R China 4.Univ Chinese Acad Sci, Dept Psychol, Beijing 101408, Peoples R China
推荐引用方式 GB/T 7714	Huang, Xiao,Sun, Yuan,Wu, Anshi,et al. Overweight or Obesity among Chinese Han People with Schizophrenia: Demographic, Clinical and Cognitive Correlations[J]. BRAIN SCIENCES,2023,13(9):11.
APA	Huang, Xiao,Sun, Yuan,Wu, Anshi,&Zhang, Xiangyang.(2023).Overweight or Obesity among Chinese Han People with Schizophrenia: Demographic, Clinical and Cognitive Correlations.BRAIN SCIENCES,13(9),11.
MLA	Huang, Xiao,et al."Overweight or Obesity among Chinese Han People with Schizophrenia: Demographic, Clinical and Cognitive Correlations".BRAIN SCIENCES 13.9(2023):11.