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Prevalence and clinical profile of comorbid anxiety in young adult patients with first-episode and drug-naive major depressive disorder | |
Luo, Rui-Chen-Xi1; Wang, Dongmei2,3; Zhou, Huixia2,3; Lang, Xiao E.4; Zhang, Xiang-Yang1,2,3 | |
第一作者 | Rui-Chen-Xi Luo |
通讯作者邮箱 | zhangxy@psych.ac.cn (xiang-yang zhang) |
心理所单位排序 | 2 |
摘要 | AimPatients with major depressive disorder (MDD) frequently have coexisting anxiety disorders. However, few studies have focused on the prevalence and risk factors of comorbid anxiety symptoms in young adult first-episode and drug-naive (FEDN) MDD patients.MethodsWe recruited 520 FEDN MDD patients and collected their demographic and clinical data. The Hamilton Depression Rating Scale (HAMD), the Hamilton Anxiety Rating Scale (HAMA) and the positive scale of the Positive and Negative Syndrome Scale (PANSS) were used to measure depressive symptoms, anxiety symptoms and psychotic symptoms, respectively.ResultsAnxiety symptoms were found in 79.6% of young adult patients. Besides, anxiety group patients had a higher prevalence of psychotic symptoms than the non-anxiety group. Anxiety symptoms were substantially related to suicide attempts in young adult patients. Logistic analysis shows that suicide attempts and total HAMD scores were significantly associated with anxiety symptoms.ConclusionsThe findings show that anxiety symptoms are common in Chinese young adult MDD patients. The anxiety group was more likely to have psychotic symptoms, suicide attempts, and more severe depressive symptoms than the non-anxiety group. Suicide attempts were associated with anxiety symptoms in young adult MDD patients, suggesting the importance of reducing anxiety symptoms in this population to prevent suicides. |
关键词 | comorbid anxiety with the major depressive disorder first episode and drug naive (FEDN) patients major depressive disorder young adults |
2023-11-27 | |
语种 | 英语 |
DOI | 10.1111/eip.13478 |
发表期刊 | EARLY INTERVENTION IN PSYCHIATRY |
ISSN | 1751-7885 |
页码 | 9 |
期刊论文类型 | 实证研究 |
收录类别 | SCI ; SSCI |
资助项目 | the CAS International Cooperation Research Program ; CAS International Cooperation Research Program[153111KYSB20190004] ; Key Research Project in Shanxi Province[201803D31098] ; Wu Jieping Medical Foundation[320.6750.18336] |
出版者 | WILEY |
WOS关键词 | AGE-OF-ONSET ; HEALTH-RELATED STIGMA ; MENTAL-HEALTH ; RISK-FACTORS ; NONANXIOUS DEPRESSION ; LIFETIME PREVALENCE ; ANXIOUS DEPRESSION ; CO-MORBIDITY ; SYMPTOMS ; CHINESE |
WOS研究方向 | Psychiatry |
WOS类目 | Psychiatry |
WOS记录号 | WOS:001108891800001 |
WOS分区 | Q3 |
资助机构 | the CAS International Cooperation Research Program ; CAS International Cooperation Research Program ; Key Research Project in Shanxi Province ; Wu Jieping Medical Foundation |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.psych.ac.cn/handle/311026/46586 |
专题 | 中国科学院心理健康重点实验室 |
通讯作者 | Zhang, Xiang-Yang |
作者单位 | 1.Anhui Med Univ, Sch Mental Hlth & Psychol Sci, Dept Psychiat, Hefei, Peoples R China 2.Chinese Acad Sci, Inst Psychol, CAS Key Lab Mental Hlth, 16 Lincui Rd, Beijing 100101, Peoples R China 3.Univ Chinese Acad Sci, Dept Psychol, Beijing, Peoples R China 4.Shanxi Med Univ, Hosp 1, Dept Psychiat, Taiyuan, Peoples R China |
通讯作者单位 | 中国科学院心理健康重点实验室 |
推荐引用方式 GB/T 7714 | Luo, Rui-Chen-Xi,Wang, Dongmei,Zhou, Huixia,et al. Prevalence and clinical profile of comorbid anxiety in young adult patients with first-episode and drug-naive major depressive disorder[J]. EARLY INTERVENTION IN PSYCHIATRY,2023:9. |
APA | Luo, Rui-Chen-Xi,Wang, Dongmei,Zhou, Huixia,Lang, Xiao E.,&Zhang, Xiang-Yang.(2023).Prevalence and clinical profile of comorbid anxiety in young adult patients with first-episode and drug-naive major depressive disorder.EARLY INTERVENTION IN PSYCHIATRY,9. |
MLA | Luo, Rui-Chen-Xi,et al."Prevalence and clinical profile of comorbid anxiety in young adult patients with first-episode and drug-naive major depressive disorder".EARLY INTERVENTION IN PSYCHIATRY (2023):9. |
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