Institutional Repository of Key Laboratory of Behavioral Science, CAS
The dual facilitatory and inhibitory effects of social pain on physical pain perception | |
Ming Zhang1,2; Xiaomin Lin1,2; Yongkang Zhi1,2; Yan Mu1,2; Yazhuo Kong1,2,3 | |
第一作者 | Ming Zhang |
通讯作者邮箱 | kongyz@psych.ac.cn |
心理所单位排序 | 1 |
摘要 | Pain is a multi-dimensional phenomenon that encompasses both physical pain experienced physiologically and social pain experienced emotionally. The interactions between them are thought to lead to increased pain load. However, the effect of social pain on physical pain perception during interactions remains unclear. Four experiments were conducted merging physical and social pains to examine the behavioral pattern and neural mechanism of the effect of social pain on physical pain perception. Seemingly paradoxical effects of social pain were observed, which both facilitated and inhibited physical pain perception under different attention orientations. Brain imaging revealed that the posterior insula encoded the facilitatory effect, whereas the frontal pole engaged in the inhibitory effect. At a higher level, the thalamus further modulated both processes, playing a switch-like role under different concern statuses of social pain. These results provide direct evidence for the dual-pathway mechanism of the effect of social pain on physical pain. |
2024-02-16 | |
语种 | 英语 |
DOI | 10.1016/j.isci.2024.108951 |
发表期刊 | iScience |
卷号 | 27期号:2页码:108951 |
期刊论文类型 | 综述 |
URL | 查看原文 |
收录类别 | SCI |
WOS分区 | Q1 |
Q分类 | Q1 |
OA状态 | OA |
研究方法 | 脑成像 |
取样对象 | 人类 |
性别 | 男 ; 女 |
年龄组 | 青年(18岁-29岁) |
被试数量 | 253 |
国家或地区 | China |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.psych.ac.cn/handle/311026/46894 |
专题 | 中国科学院行为科学重点实验室 |
通讯作者 | Yazhuo Kong |
作者单位 | 1.CAS Key Laboratory of Behavioral Science, Institute of Psychology, Chinese Academy of Sciences, Beijing 100101, China 2.Department of Psychology, University of Chinese Academy of Sciences, Beijing 100049, China 3.Wellcome Centre for Integrative Neuroimaging, FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford OX3 9DU, UK |
第一作者单位 | 中国科学院行为科学重点实验室 |
通讯作者单位 | 中国科学院行为科学重点实验室 |
推荐引用方式 GB/T 7714 | Ming Zhang,Xiaomin Lin,Yongkang Zhi,et al. The dual facilitatory and inhibitory effects of social pain on physical pain perception[J]. iScience,2024,27(2):108951. |
APA | Ming Zhang,Xiaomin Lin,Yongkang Zhi,Yan Mu,&Yazhuo Kong.(2024).The dual facilitatory and inhibitory effects of social pain on physical pain perception.iScience,27(2),108951. |
MLA | Ming Zhang,et al."The dual facilitatory and inhibitory effects of social pain on physical pain perception".iScience 27.2(2024):108951. |
条目包含的文件 | ||||||
文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
The dual facilitator(5312KB) | 期刊论文 | 出版稿 | 限制开放 | CC BY-NC-SA | 请求全文 |
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