Institutional Repository of Key Laboratory of Behavioral Science, CAS
Shared atypical spontaneous brain activity pattern in early onset schizophrenia and autism spectrum disorders: evidence from cortical surface-based analysis(Mar , 10.1007/s00787-023-02333-2, 2024) | |
Jin, Xingyue1,2; Zhang, Kun1,2; Lu, Bin3,4; Li, Xue5; Yan, Chao-Gan3,4; Du, Yasong6; Liu, Yi6; Lu, Jianping7; Luo, Xuerong1,2; Gao, Xueping1,2; Liu, Jing5 | |
第一作者 | Jie Tang |
通讯作者邮箱 | luoxuerong@csu.edu.cn (xuerong luo ) ; xuepinggao@csu.edu.cn (xueping gao) ; ljyuch@bjmu.edu.cn (jing liu ) |
心理所单位排序 | 3 |
摘要 | Schizophrenia and autism spectrum disorders (ASD) were considered as two neurodevelopmental disorders and had shared clinical features. we hypothesized that they have some common atypical brain functions and the purpose of this study was to explored the shared brain spontaneous activity strength alterations in early onset schizophrenia (EOS) and ASD in the children and adolescents with a multi-center large-sample study. A total of 171 EOS patients (aged 14.25 ± 1.87), 188 ASD patients (aged 9.52 ± 5.13), and 107 healthy controls (aged 11.52 ± 2.82) had scanned with Resting-fMRI and analyzed surface-based amplitude of low-frequency fuctuations (ALFF). Results showed that both EOS and ASD had hypoactivity in the primary sensorimotor regions (bilateral primary and early visual cortex, left ventral visual stream, left primary auditory cortex) and hyperactivity in the high-order transmodal regions (bilateral SFL, bilateral DLPFC, right frontal eye felds), and bilateral thalamus. EOS had more severe abnormality than ASD. This study revealed shared functional abnormalities in the primary sensorimotor regions and the high-order transmodal regions in EOS and ASD, which provided neuroimaging evidence of common changes in EOS and ASD, and may help with better early recognition and precise treatment for EOS and ASD. |
关键词 | Schizophrenia EOS ASD Autism fMRI ALFF Cortex |
2024-03-06 | |
语种 | 英语 |
DOI | 10.1007/s00787-024-02409-7 |
发表期刊 | EUROPEAN CHILD & ADOLESCENT PSYCHIATRY |
ISSN | 1018-8827 |
页码 | 1 |
期刊论文类型 | 实证研究 |
收录类别 | SCI ; SSCI |
出版者 | SPRINGER |
WOS研究方向 | Psychology ; Pediatrics ; Psychiatry |
WOS类目 | Psychology, Developmental ; Pediatrics ; Psychiatry |
WOS记录号 | WOS:001177077900001 |
WOS分区 | Q1 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.psych.ac.cn/handle/311026/47333 |
专题 | 中国科学院行为科学重点实验室 |
通讯作者 | Luo, Xuerong; Gao, Xueping; Liu, Jing |
作者单位 | 1.Cent South Univ, Xiangya Hosp 2, Natl Clin Res Ctr Mental Disorders, Dept Psychiat, Changsha 410011, Hunan, Peoples R China 2.Cent South Univ, Xiangya Hosp 2, Natl Ctr Mental Disorders, Changsha 410011, Hunan, Peoples R China 3.Inst Psychol, CAS Key Lab Behav Sci, Beijing 100101, Peoples R China 4.Univ Chinese Acad Sci, Dept Psychol, Beijing 100101, Peoples R China 5.Peking Univ, Peking Univ Sixth Hosp, Peking Univ Inst Mental Hlth, Natl Clin Res Ctr Mental Disorders,NHC Key Lab Men, 51 Huayuan Rd, Beijing 100191, Peoples R China 6.Shanghai Mental Hlth Ctr, 600 Wanping Nan Rd, Shanghai, Peoples R China 7.Shenzhen Kangning Hosp, Shenzhen Mental Hlth Ctr, Dept Child Psychiat, Shenzhen, Peoples R China |
推荐引用方式 GB/T 7714 | Jin, Xingyue,Zhang, Kun,Lu, Bin,et al. Shared atypical spontaneous brain activity pattern in early onset schizophrenia and autism spectrum disorders: evidence from cortical surface-based analysis(Mar , 10.1007/s00787-023-02333-2, 2024)[J]. EUROPEAN CHILD & ADOLESCENT PSYCHIATRY,2024:1. |
APA | Jin, Xingyue.,Zhang, Kun.,Lu, Bin.,Li, Xue.,Yan, Chao-Gan.,...&Liu, Jing.(2024).Shared atypical spontaneous brain activity pattern in early onset schizophrenia and autism spectrum disorders: evidence from cortical surface-based analysis(Mar , 10.1007/s00787-023-02333-2, 2024).EUROPEAN CHILD & ADOLESCENT PSYCHIATRY,1. |
MLA | Jin, Xingyue,et al."Shared atypical spontaneous brain activity pattern in early onset schizophrenia and autism spectrum disorders: evidence from cortical surface-based analysis(Mar , 10.1007/s00787-023-02333-2, 2024)".EUROPEAN CHILD & ADOLESCENT PSYCHIATRY (2024):1. |
条目包含的文件 | ||||||
文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
Shared atypical spon(726KB) | 期刊论文 | 出版稿 | 限制开放 | CC BY-NC-SA | 请求全文 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论