Gender differences in the prevalence and clinical correlates of suicide attempts in young first-episode drug-na?ve major depressive disorder patients with thyroid dysfunction

doi:10.1186/s12888-024-06332-8

PSYCH OpenIR

	Gender differences in the prevalence and clinical correlates of suicide attempts in young first-episode drug-na?ve major depressive disorder patients with thyroid dysfunction
	Liu, Luyu 1; Zhou, Jian 1; Song, Xinran 1; Luo, Guowei 1; Peng, Min 1; Zhang, Xiangyang 2,3
通讯作者	Peng, Min(mindy_peng@163.com) ; Zhang, Xiangyang(zhangxy@psych.ac.cn)
摘要	Thyroid dysfunction is commonly seen in major depressive disorder (MDD), and is particularly prevalent in female patients. Moreover, gender differences occur in many aspects of MDD, including suicide attempts (SAs). We aimed to explore gender differences in the prevalence and clinical correlates of SAs in young first-episode drug-na & iuml;ve MDD patients with thyroid dysfunction, which have not yet been reported. We recruited 509 patients in this study. Demographic and clinical characteristics were collected. We used HAMD-17, HAMA-14, the positive subscale of PANSS, and CGI-S to assess every participant. We found no significant difference in the prevalence of SAs between male and female subgroup. Gender differences in factors associated with SAs were found with anxiety, body mass index, serum anti-thyroid antibodies (A-TPO), and free triiodothyronine levels in male patients and anxiety, CGI-S score, and A-TPO in female patients. We found no gender differences in the prevalence of SAs; however, there were gender differences in several clinical correlates of SAs, highlighting specific strategies to avoid SAs in male and female MDD patients.
关键词	Major depressive disorder Suicide attempts Gender differences First episode and drug na & iuml ve patients
	2024-12-04
语种	英语
DOI	10.1186/s12888-024-06332-8
发表期刊	BMC PSYCHIATRY
卷号	24 期号:1 页码:11
收录类别	SCI
资助项目	Health Science and technology program of Nanshan District
出版者	BMC
WOS关键词	RISK-FACTORS ; SEX-DIFFERENCES ; HORMONE-LEVELS ; IDEATION ; ANXIETY ; SCALE ; ASSOCIATION ; EUROPE
WOS研究方向	Psychiatry
WOS类目	Psychiatry
WOS记录号	WOS:001369291800003
资助机构	Health Science and technology program of Nanshan District
引用统计
文献类型	期刊论文
条目标识符	https://ir.psych.ac.cn/handle/311026/48687
通讯作者	Peng, Min; Zhang, Xiangyang
作者单位	1.Shenzhen Nanshan Peoples Hosp, Dept Psychiat, 89 Taoyuan Rd, Shenzhen 518052, Peoples R China 2.Chinese Acad Sci, Inst Psychol, CAS Key Lab Mental Hlth, 16 Lincui Rd, Beijing 100101, Peoples R China 3.Univ Chinese Acad Sci, Dept Psychol, Beijing, Peoples R China
推荐引用方式 GB/T 7714	Liu, Luyu,Zhou, Jian,Song, Xinran,et al. Gender differences in the prevalence and clinical correlates of suicide attempts in young first-episode drug-na?ve major depressive disorder patients with thyroid dysfunction[J]. BMC PSYCHIATRY,2024,24(1):11.
APA	Liu, Luyu,Zhou, Jian,Song, Xinran,Luo, Guowei,Peng, Min,&Zhang, Xiangyang.(2024).Gender differences in the prevalence and clinical correlates of suicide attempts in young first-episode drug-na?ve major depressive disorder patients with thyroid dysfunction.BMC PSYCHIATRY,24(1),11.
MLA	Liu, Luyu,et al."Gender differences in the prevalence and clinical correlates of suicide attempts in young first-episode drug-na?ve major depressive disorder patients with thyroid dysfunction".BMC PSYCHIATRY 24.1(2024):11.