A mobile device-based game prototype for ADHD: development and preliminary feasibility testing

doi:10.1038/s41398-024-02964-2

PSYCH OpenIR

	A mobile device-based game prototype for ADHD: development and preliminary feasibility testing
	Luo, Jie 1; Li, Fenghua 2; Wu, Yuanzhen 1; Liu, Xuanang 2; Zheng, Qingyi 3; Qi, Yanjie 1; Huang, Huanhuan 1; Xu, Gaoyang 1; Liu, Zhengkui 2; He, Fan 1; Zheng, Yi 1
通讯作者	He, Fan(hf981207@163.com) ; Zheng, Yi(yizheng@ccmu.edu.cn)
摘要	This research aimed to devise and assess a mobile game therapy software for children with Attention-Deficit/Hyperactivity Disorder (ADHD), as well as evaluating its suitability and effectiveness in improving the cognitive ability of typically developing children. The study encompassed 55 children diagnosed with ADHD and 55 neurotypical children. Initial assessments involved ADHD-related scales, computerized tests for information processing, and physiological-psychological evaluations. After a 4-week home-based game intervention, participants underwent re-evaluation using baseline measures and provided feedback on treatment satisfaction. Considering the small proportion of study participants who dropped out, data was analyzed using both the Intention-to-Treat (ITT) analysis and the Per-protocol (PP) analysis. The trial was registered at ClinicalTrials.gov (NCT06181747). In ITT analysis, post-intervention analysis using linear mixed models indicated that the ADHD group improved significantly more than the neurotypical group particularly in Continuous Performance Test (CPT) accuracy (B = -23.92, p < 0.001) and reaction time (B = 86.08, p < 0.01), along with enhancements in anti-saccade (B = -10.65, p < 0.05) and delayed-saccade tasks (B = 0.34, p < 0.05). A reduction in parent-rated SNAP-IV scores was also observed (B = 0.43, p < 0.01). In PP analysis, paired-sample t-tests suggested that the ADHD group had significant changes pre- and post-intervention, in terms of CPT Accuracy (t = -7.62, p < 0.01), Anti-saccade task Correct Rate (t = -3.90, p < 0.01) and SNAP-IV scores (t = -4,64, p < 0.01). However, no significant changes post-intervention were observed in the neurotypical group. Survey feedback highlighted a strong interest in the games across both groups, though ADHD participants found the game more challenging. Parents of ADHD children reported perceived benefits and a willingness to continue the game therapy, unlike the neurotypical group's parents. The findings advocated for the integration of serious video games as a complementary tool in ADHD treatment strategies, demonstrating the potential to augment attentional abilities and alleviate clinical symptoms. However, a randomized controlled trial (RCT) is needed to further verify its efficacy.
	2024-06-10
语种	英语
DOI	10.1038/s41398-024-02964-2
发表期刊	TRANSLATIONAL PSYCHIATRY
ISSN	2158-3188
卷号	14 期号:1 页码:11
收录类别	SCI
资助项目	Beijing Hospitals Authority Clinical Medicine Development of Special Funding Support, No: ZYLX202128; High-level Public Health Technology Talent Construction Project, No: Discipline Backbone-01-029; High-level Public Health Technology Talent Construction P
出版者	SPRINGERNATURE
WOS关键词	WORKING-MEMORY ; CHILDREN ; PERFORMANCE ; YOUTH
WOS研究方向	Psychiatry
WOS类目	Psychiatry
WOS记录号	WOS:001243815000003
资助机构	Beijing Hospitals Authority Clinical Medicine Development of Special Funding Support, No: ZYLX202128; High-level Public Health Technology Talent Construction Project, No: Discipline Backbone-01-029; High-level Public Health Technology Talent Construction P
引用统计
文献类型	期刊论文
条目标识符	https://ir.psych.ac.cn/handle/311026/49336
通讯作者	He, Fan; Zheng, Yi
作者单位	1.Capital Med Univ, Beijing Anding Hosp, Natl Clin Res Ctr Mental Disorders, Beijing Key Lab Mental Disorders,Beijing Inst Brai, Beijing, Peoples R China 2.Chinese Acad Sci, Key Lab Mental Hlth, Inst Psychol, Beijing, Peoples R China 3.UCL, Inst Educ, Dept Psychol & Human Dev, London, England
推荐引用方式 GB/T 7714	Luo, Jie,Li, Fenghua,Wu, Yuanzhen,et al. A mobile device-based game prototype for ADHD: development and preliminary feasibility testing[J]. TRANSLATIONAL PSYCHIATRY,2024,14(1):11.
APA	Luo, Jie.,Li, Fenghua.,Wu, Yuanzhen.,Liu, Xuanang.,Zheng, Qingyi.,...&Zheng, Yi.(2024).A mobile device-based game prototype for ADHD: development and preliminary feasibility testing.TRANSLATIONAL PSYCHIATRY,14(1),11.
MLA	Luo, Jie,et al."A mobile device-based game prototype for ADHD: development and preliminary feasibility testing".TRANSLATIONAL PSYCHIATRY 14.1(2024):11.