Activation of the hypothalamus characterizes the response to acupuncture stimulation in heroin addicts
Liu, Sheng; Zhou, Wenhua; Ruan, Xingzhong; Li, Ronghui; Lee, Tatia; Weng, Xuchu; Hu, Jun; Yang, Guodong; W. H. Zhou
2007-06-29
发表期刊NEUROSCIENCE LETTERS
ISSN0304-3940
文章类型Article
卷号421期号:3页码:203-208
摘要Acupuncture stimulation elicited a composite of sensations termed deqi that is related to clinical efficacy. Neurobiological studies have identified the hypothalamus as an important component in mediating the deqi. Functional changes in hypothalamus persist after abstinence in addicts. We investigated the activation in the hypothalamus associated with acupuncture stimulation in healthy volunteers and heroin addicts by fMRI. Cortisol level and psychophysical responses, including the deqi sensation (an acupuncture effect of needle-manipulation), anxiety, and sharp pain, were also assessed. The activation of the hypothalamus was more robust in the addicts than that in the healthy subjects during acupuncture stimulation. The deqi scores of the heroin addicts were significantly higher than those of the healthy subjects during acupuncture treatment. An acupuncture sensation scale predicted the activation of the hypothalamus associated with the deqi sensation.; Acupuncture stimulation elicited a composite of sensations termed deqi that is related to clinical efficacy. Neurobiological studies have identified the hypothalamus as an important component in mediating the deqi. Functional changes in hypothalamus persist after abstinence in addicts. We investigated the activation in the hypothalamus associated with acupuncture stimulation in healthy volunteers and heroin addicts by fMRI. Cortisol level and psychophysical responses, including the deqi sensation (an acupuncture effect of needle-manipulation), anxiety, and sharp pain, were also assessed. The activation of the hypothalamus was more robust in the addicts than that in the healthy subjects during acupuncture stimulation. The deqi scores of the heroin addicts were significantly higher than those of the healthy subjects during acupuncture treatment. An acupuncture sensation scale predicted the activation of the hypothalamus associated with the deqi sensation. (c) 2007 Elsevier Ireland Ltd. All rights reserved.
关键词acupuncture hypothalamus cortisol heroin addicts
学科领域生理心理学/生物心理学
收录类别SCI
语种英语
WOS记录号WOS:000248152100004
引用统计
被引频次:28[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.psych.ac.cn/handle/311026/5153
专题中国科学院心理研究所回溯数据库(1956-2010)
通讯作者W. H. Zhou
作者单位1.Ningbo Addict Res & Treatment Ctr, Ningbo, Peoples R China
2.Ningbo First Peoples Hosp, Dept MRI, Ningbo 315010, Peoples R China
3.Univ Hong Kong, Neuropsychol Lab, Hong Kong, Peoples R China
4.Chinese Acad Sci, Inst Psychol, Beijing 100864, Peoples R China
5.Shanghai Univ Tradit Chinese Med, Shanghai, Peoples R China
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Liu, Sheng,Zhou, Wenhua,Ruan, Xingzhong,et al. Activation of the hypothalamus characterizes the response to acupuncture stimulation in heroin addicts[J]. NEUROSCIENCE LETTERS,2007,421(3):203-208.
APA Liu, Sheng.,Zhou, Wenhua.,Ruan, Xingzhong.,Li, Ronghui.,Lee, Tatia.,...&W. H. Zhou.(2007).Activation of the hypothalamus characterizes the response to acupuncture stimulation in heroin addicts.NEUROSCIENCE LETTERS,421(3),203-208.
MLA Liu, Sheng,et al."Activation of the hypothalamus characterizes the response to acupuncture stimulation in heroin addicts".NEUROSCIENCE LETTERS 421.3(2007):203-208.
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