Comparison of Hypoglycemic Activity of Trace Elements Absorbed in Fermented Mushroom of Coprinus comatus
Lv, Yingtao2; Han, Linna3; Yuan, Chao4; Guo, Jianyou1; J. Y. Guo
2009-11-01
发表期刊BIOLOGICAL TRACE ELEMENT RESEARCH
ISSN0163-4984
文章类型Article
卷号131期号:2页码:177-185
摘要The effect of fermented mushroom of Coprinus comatus rich in trace elements, including vanadium, chromium, zinc, magnesium, copper, iron, and nickel, on glycemic metabolism was studied in this paper. Alloxan-induced hyperglycemic mice were used in the study. The blood glucose, glycohemoglobin, and glycogen synthesis of the mice were analyzed, respectively. At the same time, the gluconeogenesis of the normal mice was also determined. After the mice were administered (ig) with C. comatus rich in vanadium (CCRV), the blood glucose and the glycohemoglobin of alloxan-induced hyperglycemic mice decreased (p < 0.05, p < 0.01), glycogen synthesis of alloxan-induced hyperglycemic mice elevated (p < 0.01), the gluconeogenesis of the normal mice was inhibited (p < 0.01), and the sugar tolerance of the normal mice was improved. However, the same result did not occur in other groups. Vanadium at lower doses in combination with C. comatus induced significant effect on glycemic metabolism in mice.; The effect of fermented mushroom of Coprinus comatus rich in trace elements, including vanadium, chromium, zinc, magnesium, copper, iron, and nickel, on glycemic metabolism was studied in this paper. Alloxan-induced hyperglycemic mice were used in the study. The blood glucose, glycohemoglobin, and glycogen synthesis of the mice were analyzed, respectively. At the same time, the gluconeogenesis of the normal mice was also determined. After the mice were administered (ig) with C. comatus rich in vanadium (CCRV), the blood glucose and the glycohemoglobin of alloxan-induced hyperglycemic mice decreased (p < 0.05, p < 0.01), glycogen synthesis of alloxan-induced hyperglycemic mice elevated (p < 0.01), the gluconeogenesis of the normal mice was inhibited (p < 0.01), and the sugar tolerance of the normal mice was improved. However, the same result did not occur in other groups. Vanadium at lower doses in combination with C. comatus induced significant effect on glycemic metabolism in mice.
关键词Trace elements Blood glucose HbA1c Glycogen Gluconeogenesis Sugar tolerance
学科领域微生物学
收录类别SCI
语种英语
WOS记录号WOS:000270323100008
引用统计
文献类型期刊论文
条目标识符http://ir.psych.ac.cn/handle/311026/5263
专题中国科学院心理研究所回溯数据库(1956-2010)
通讯作者J. Y. Guo
作者单位1.Chinese Acad Sci, Key Lab Mental Hlth, Inst Psychol, Beijing 100101, Peoples R China
2.Qingdao Univ Sci & Technol, Coll Chem Engn, Qingdao 266042, Peoples R China
3.Shandong Univ Tradit Chinese Med, Sch Pharm, Jinan 250355, Peoples R China
4.Shandong Med Coll, Jinan 250002, Peoples R China
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Lv, Yingtao,Han, Linna,Yuan, Chao,et al. Comparison of Hypoglycemic Activity of Trace Elements Absorbed in Fermented Mushroom of Coprinus comatus[J]. BIOLOGICAL TRACE ELEMENT RESEARCH,2009,131(2):177-185.
APA Lv, Yingtao,Han, Linna,Yuan, Chao,Guo, Jianyou,&J. Y. Guo.(2009).Comparison of Hypoglycemic Activity of Trace Elements Absorbed in Fermented Mushroom of Coprinus comatus.BIOLOGICAL TRACE ELEMENT RESEARCH,131(2),177-185.
MLA Lv, Yingtao,et al."Comparison of Hypoglycemic Activity of Trace Elements Absorbed in Fermented Mushroom of Coprinus comatus".BIOLOGICAL TRACE ELEMENT RESEARCH 131.2(2009):177-185.
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