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Comparison of Hypoglycemic Activity of Trace Elements Absorbed in Fermented Mushroom of Coprinus comatus
Lv, Yingtao2; Han, Linna3; Yuan, Chao4; Guo, Jianyou1; J. Y. Guo
2009-11-01
Source PublicationBIOLOGICAL TRACE ELEMENT RESEARCH
ISSN0163-4984
SubtypeArticle
Volume131Issue:2Pages:177-185
AbstractThe effect of fermented mushroom of Coprinus comatus rich in trace elements, including vanadium, chromium, zinc, magnesium, copper, iron, and nickel, on glycemic metabolism was studied in this paper. Alloxan-induced hyperglycemic mice were used in the study. The blood glucose, glycohemoglobin, and glycogen synthesis of the mice were analyzed, respectively. At the same time, the gluconeogenesis of the normal mice was also determined. After the mice were administered (ig) with C. comatus rich in vanadium (CCRV), the blood glucose and the glycohemoglobin of alloxan-induced hyperglycemic mice decreased (p < 0.05, p < 0.01), glycogen synthesis of alloxan-induced hyperglycemic mice elevated (p < 0.01), the gluconeogenesis of the normal mice was inhibited (p < 0.01), and the sugar tolerance of the normal mice was improved. However, the same result did not occur in other groups. Vanadium at lower doses in combination with C. comatus induced significant effect on glycemic metabolism in mice.; The effect of fermented mushroom of Coprinus comatus rich in trace elements, including vanadium, chromium, zinc, magnesium, copper, iron, and nickel, on glycemic metabolism was studied in this paper. Alloxan-induced hyperglycemic mice were used in the study. The blood glucose, glycohemoglobin, and glycogen synthesis of the mice were analyzed, respectively. At the same time, the gluconeogenesis of the normal mice was also determined. After the mice were administered (ig) with C. comatus rich in vanadium (CCRV), the blood glucose and the glycohemoglobin of alloxan-induced hyperglycemic mice decreased (p < 0.05, p < 0.01), glycogen synthesis of alloxan-induced hyperglycemic mice elevated (p < 0.01), the gluconeogenesis of the normal mice was inhibited (p < 0.01), and the sugar tolerance of the normal mice was improved. However, the same result did not occur in other groups. Vanadium at lower doses in combination with C. comatus induced significant effect on glycemic metabolism in mice.
KeywordTrace elements Blood glucose HbA1c Glycogen Gluconeogenesis Sugar tolerance
Subject Area微生物学
Indexed BySCI
Language英语
WOS IDWOS:000270323100008
Citation statistics
Cited Times:12[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.psych.ac.cn/handle/311026/5263
Collection中国科学院心理研究所回溯数据库(1956-2010)
Corresponding AuthorJ. Y. Guo
Affiliation1.Chinese Acad Sci, Key Lab Mental Hlth, Inst Psychol, Beijing 100101, Peoples R China
2.Qingdao Univ Sci & Technol, Coll Chem Engn, Qingdao 266042, Peoples R China
3.Shandong Univ Tradit Chinese Med, Sch Pharm, Jinan 250355, Peoples R China
4.Shandong Med Coll, Jinan 250002, Peoples R China
Recommended Citation
GB/T 7714
Lv, Yingtao,Han, Linna,Yuan, Chao,et al. Comparison of Hypoglycemic Activity of Trace Elements Absorbed in Fermented Mushroom of Coprinus comatus[J]. BIOLOGICAL TRACE ELEMENT RESEARCH,2009,131(2):177-185.
APA Lv, Yingtao,Han, Linna,Yuan, Chao,Guo, Jianyou,&J. Y. Guo.(2009).Comparison of Hypoglycemic Activity of Trace Elements Absorbed in Fermented Mushroom of Coprinus comatus.BIOLOGICAL TRACE ELEMENT RESEARCH,131(2),177-185.
MLA Lv, Yingtao,et al."Comparison of Hypoglycemic Activity of Trace Elements Absorbed in Fermented Mushroom of Coprinus comatus".BIOLOGICAL TRACE ELEMENT RESEARCH 131.2(2009):177-185.
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