Decreased gyrification in major depressive disorder
Zhang, Yuanchao1; Yu, Chunshui3; Zhou, Yuan1,4; Li, Kuncheng3; Li, Chong1; Jiang, Tianzi1; T. Z. Jiang
2009-03-04
发表期刊NEUROREPORT
ISSN0959-4965
文章类型Article
卷号20期号:4页码:378-380
摘要Structural and functional abnormalities have been extensively reported in major depressive disorder, but possible changes in cortical folding have not yet been explored in this disorder. This study investigated this issue in major depressive disorder using the local gyrification index. High-resolution magnetic resonance imaging was performed in 18 patients with first-episode major depressive disorder and 18 age-matched and sex-matched healthy individuals. The local gyrification index was applied to detect brain areas with abnormal cortical folding in major depressive disorder. Compared with healthy participants, patients with major depressive disorder showed significantly decreased local gyrification index in the bilateral mid-posterior cingulate, insula, and orbital frontal cortices, the left anterior cingulate cortex, and the right temporal operculum.; Structural and functional abnormalities have been extensively reported in major depressive disorder, but possible changes in cortical folding have not yet been explored in this disorder. This study investigated this issue in major depressive disorder using the local gyrification index. High-resolution magnetic resonance imaging was performed in 18 patients with first-episode major depressive disorder and 18 age-matched and sex-matched healthy individuals. The local gyrification index was applied to detect brain areas with abnormal cortical folding in major depressive disorder. Compared with healthy participants, patients with major depressive disorder showed significantly decreased local gyrification index in the bilateral mid-posterior cingulate, insula, and orbital frontal cortices, the left anterior cingulate cortex, and the right temporal operculum. NeuroReport 20:378-380 (C) 2009 Wolters Kluwer Health | Lippincott Williams & Wilkins.
关键词complexity connectivity cortical folding local gyrification index magnetic resonance imaging major depressive disorder
学科领域变态心理学
收录类别SCI
语种英语
WOS记录号WOS:000264516700006
引用统计
被引频次:25[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.psych.ac.cn/handle/311026/5299
专题中国科学院心理研究所回溯数据库(1956-2010)
通讯作者T. Z. Jiang
作者单位1.Zhejiang Univ, Dept Math, Hangzhou 310027, Zhejiang, Peoples R China
2.Chinese Acad Sci, Natl Lab Pattern Recognit, Inst Automat, Beijing 100190, Peoples R China
3.Capital Med Univ, Xuanwu Hosp, Dept Radiol, Beijing, Peoples R China
4.Chinese Acad Sci, Inst Psychol, Ctr Social & Econ Behav, Beijing 100190, Peoples R China
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GB/T 7714
Zhang, Yuanchao,Yu, Chunshui,Zhou, Yuan,et al. Decreased gyrification in major depressive disorder[J]. NEUROREPORT,2009,20(4):378-380.
APA Zhang, Yuanchao.,Yu, Chunshui.,Zhou, Yuan.,Li, Kuncheng.,Li, Chong.,...&T. Z. Jiang.(2009).Decreased gyrification in major depressive disorder.NEUROREPORT,20(4),378-380.
MLA Zhang, Yuanchao,et al."Decreased gyrification in major depressive disorder".NEUROREPORT 20.4(2009):378-380.
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