Decreased gyrification in major depressive disorder

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	Decreased gyrification in major depressive disorder
	Zhang, Yuanchao 1; Yu, Chunshui 3; Zhou, Yuan1,4 ; Li, Kuncheng 3; Li, Chong1 ; Jiang, Tianzi 1; T. Z. Jiang
摘要	Structural and functional abnormalities have been extensively reported in major depressive disorder, but possible changes in cortical folding have not yet been explored in this disorder. This study investigated this issue in major depressive disorder using the local gyrification index. High-resolution magnetic resonance imaging was performed in 18 patients with first-episode major depressive disorder and 18 age-matched and sex-matched healthy individuals. The local gyrification index was applied to detect brain areas with abnormal cortical folding in major depressive disorder. Compared with healthy participants, patients with major depressive disorder showed significantly decreased local gyrification index in the bilateral mid-posterior cingulate, insula, and orbital frontal cortices, the left anterior cingulate cortex, and the right temporal operculum.; Structural and functional abnormalities have been extensively reported in major depressive disorder, but possible changes in cortical folding have not yet been explored in this disorder. This study investigated this issue in major depressive disorder using the local gyrification index. High-resolution magnetic resonance imaging was performed in 18 patients with first-episode major depressive disorder and 18 age-matched and sex-matched healthy individuals. The local gyrification index was applied to detect brain areas with abnormal cortical folding in major depressive disorder. Compared with healthy participants, patients with major depressive disorder showed significantly decreased local gyrification index in the bilateral mid-posterior cingulate, insula, and orbital frontal cortices, the left anterior cingulate cortex, and the right temporal operculum. NeuroReport 20:378-380 (C) 2009 Wolters Kluwer Health \| Lippincott Williams & Wilkins.
关键词	complexity connectivity cortical folding local gyrification index magnetic resonance imaging major depressive disorder
学科领域	变态心理学
	2009-03-04
语种	英语
发表期刊	NEUROREPORT
ISSN	0959-4965
卷号	20 期号:4 页码:378-380
期刊论文类型	Article
收录类别	SCI
WOS记录号	WOS:000264516700006
引用统计	被引频次：49[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.psych.ac.cn/handle/311026/5299
专题	中国科学院心理研究所回溯数据库(1956-2010)
通讯作者	T. Z. Jiang
作者单位	1.Zhejiang Univ, Dept Math, Hangzhou 310027, Zhejiang, Peoples R China 2.Chinese Acad Sci, Natl Lab Pattern Recognit, Inst Automat, Beijing 100190, Peoples R China 3.Capital Med Univ, Xuanwu Hosp, Dept Radiol, Beijing, Peoples R China 4.Chinese Acad Sci, Inst Psychol, Ctr Social & Econ Behav, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Yuanchao,Yu, Chunshui,Zhou, Yuan,et al. Decreased gyrification in major depressive disorder[J]. NEUROREPORT,2009,20(4):378-380.
APA	Zhang, Yuanchao.,Yu, Chunshui.,Zhou, Yuan.,Li, Kuncheng.,Li, Chong.,...&T. Z. Jiang.(2009).Decreased gyrification in major depressive disorder.NEUROREPORT,20(4),378-380.
MLA	Zhang, Yuanchao,et al."Decreased gyrification in major depressive disorder".NEUROREPORT 20.4(2009):378-380.

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