PSYCH OpenIR  > 中国科学院心理研究所回溯数据库(1956-2010)
The effect of emotional stress on the primary humoral immunity of rats
Shao, F; Lin, WJ; Wang, WW; Washington, WC; Zheng, L
2003-06-01
Source PublicationJOURNAL OF PSYCHOPHARMACOLOGY
ISSN0269-8811
SubtypeArticle
Volume17Issue:2Pages:179-183
Abstract

The effect of exposure to emotional stress on humoral immune function after injection with ovalbumin, a novel antigen, was studied in adult male Wistar rats. Emotional stress was induced by randomly giving empty water bottles to rats trained to drink water at set times. The results showed that emotional stress induced the decrease in spleen weight and specific immunoglobulin G antibody level to ovalbumin, and increased levels of epinephrine, norepinephrine and corticosterone. A decrease of antibody levels correlated negatively with an increase in plasma norepinephrine levels. These findings suggest that emotional stress can modulate immune function, and that sympathetic nervous system may be involved in this immunomodulation.

;

The effect of exposure to emotional stress on humoral immune function after injection with ovalbumin, a novel antigen, was studied in adult male Wistar rats. Emotional stress was induced by randomly giving empty water bottles to rats trained to drink water at set times. The results showed that emotional stress induced the decrease in spleen weight and specific immunoglobulin G antibody level to ovalbumin, and increased levels of epinephrine, norepinephrine and corticosterone. A decrease of antibody levels correlated negatively with an increase in plasma norepinephrine levels. These findings suggest that emotional stress can modulate immune function, and that sympathetic nervous system may be involved in this immunomodulation.

Keywordantibody emotional stress empty water bottles immunomodulation sympathetic nervous system
Subject Area生理心理学/生物心理学
Indexed BySCI
Language英语
WOS IDWOS:000183624700005
Citation statistics
Document Type期刊论文
Identifierhttp://ir.psych.ac.cn/handle/311026/5747
Collection中国科学院心理研究所回溯数据库(1956-2010)
Affiliation1.Chinese Acad Sci, Inst Psychol, Brain Behav Res Ctr, Beijing 100101, Peoples R China
2.Peking Univ, Dept Psychol, Beijing, Peoples R China
Recommended Citation
GB/T 7714
Shao, F,Lin, WJ,Wang, WW,et al. The effect of emotional stress on the primary humoral immunity of rats[J]. JOURNAL OF PSYCHOPHARMACOLOGY,2003,17(2):179-183.
APA Shao, F,Lin, WJ,Wang, WW,Washington, WC,&Zheng, L.(2003).The effect of emotional stress on the primary humoral immunity of rats.JOURNAL OF PSYCHOPHARMACOLOGY,17(2),179-183.
MLA Shao, F,et al."The effect of emotional stress on the primary humoral immunity of rats".JOURNAL OF PSYCHOPHARMACOLOGY 17.2(2003):179-183.
Files in This Item:
File Name/Size DocType Version Access License
The effect of emotio(191KB)期刊论文作者接受稿限制开放CC BY-NC-SAView Application Full Text
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Shao, F]'s Articles
[Lin, WJ]'s Articles
[Wang, WW]'s Articles
Baidu academic
Similar articles in Baidu academic
[Shao, F]'s Articles
[Lin, WJ]'s Articles
[Wang, WW]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Shao, F]'s Articles
[Lin, WJ]'s Articles
[Wang, WW]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: The effect of emotional stress on the primary humoral immunity of rats.pdf
Format: Adobe PDF
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.