Corticosterone reinforces motivation for drug-seeking in morphine-dependent rats in Morris maze performance

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	Corticosterone reinforces motivation for drug-seeking in morphine-dependent rats in Morris maze performance
	N. Sul; J. Chen; J. Hu; C. Sandi; J. J. Yang; X. Y. Yang
	2000
会议名称	会议论文
页码	132-132
会议日期	2000
会议地点	Stockholm
摘要	Corticosterone and morphine's effect on motivational intensity for drug-seeking was investigated. Rats were given intraperitoneal injections with morphine, corticosterone, morphine plus corticosterone immediately after trained without platform. Then in the maze with platform, only the rats avoiding the platform for 1min were given the drugs. Results indicated that corticosterone plus morphine significantly increased the latency of locating the platform over 4,8,16 day withdrawal periods, while with morphine alone the effect occurred only on the 4th day. Possible mechanisms of the facilitating effects of corticosterone depend on increasing sensitivity to morphine or enhancing retention of the propensity of drug intake.
会议主办者	IUPsyS
学科领域	医学心理学
收录类别	SSCI
语种	英语
WOS记录号	WOS:000088388801280
引用统计
文献类型	会议论文
条目标识符	http://ir.psych.ac.cn/handle/311026/5897
专题	中国科学院心理研究所回溯数据库(1956-2010)
推荐引用方式 GB/T 7714	N. Sul,J. Chen,J. Hu,et al. Corticosterone reinforces motivation for drug-seeking in morphine-dependent rats in Morris maze performance[C],2000:132-132.