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b-Adrenergic receptor involvement in emotional stress-induced
W. M. Wang; W. J. Lin
Conference Name会议论文
Conference Date2004
Conference PlaceBeijing
AbstractUsing a new established emotional stress model, our previous work has demonstrated that exposure of chronic stress to rats immunized with ovalbumine induced a decrease of the level of specific anti-ovalbumine IgG antibody production. The present study assessed the involvement of the b-adrenergic receptor (b-ADR) in the stress-induced immune suppressive effect. Rats were administered the nonselective b-ADR antagonist propranolol in doses of 1, 5 or 15mg/kg i.p 30min before each stress procedure. Propranolol in doses of 5 and 15mg/kg but not 1mg/kg completely reversed stress-induced immunosuppression. The results suggest that b-ADR is involved in the stress-induced suppression of humoral immune function.
Funding OrganizationIUPsyS
Subject Area生理心理学/生物心理学
Indexed BySSCI
WOS IDWOS:000226118001287
Citation statistics
Document Type会议论文
Recommended Citation
GB/T 7714
W. M. Wang,W. J. Lin. b-Adrenergic receptor involvement in emotional stress-induced[C],2004:142-142.
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