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Effect of corticosterone on morphine-induced psychomotor effect and its sensitization
D. M. Wang; C. Y. Liu; Y. H. Li; X. G. Zheng; N. Sui
2004
Conference Name会议论文
Pages297-297
Conference Date2004
Conference PlaceBeijing
AbstractPrevious research demonstrated important roles of stress in behavioral effects of drug abuse. However, whether extraneous stress factors could differentially modulate morphine psychomotor effect and its sensitization is still unknown. This study examined the influence of corticosterone on the acute effect of morphine and its sensitization. Morphine (2 mg.kg-1 i.p.) enhanced the locomotor activity and formed behavioral sensitization upon repeated exposure. Corticosterone (5 mg.kg-1 i.p.) increased morphine psychomotor effect but played null role in the modulation of its sensitization. These results indicated that stress exposure promoted morphine acute psychomotor effect but did not affect the development of morphine sensitization.
Funding OrganizationIUPsyS
Subject Area生理心理学/生物心理学
Indexed BySSCI
Language英语
WOS IDWOS:000226118002707
Citation statistics
Document Type会议论文
Identifierhttp://ir.psych.ac.cn/handle/311026/6253
Collection中国科学院心理研究所回溯数据库(1956-2010)
Recommended Citation
GB/T 7714
D. M. Wang,C. Y. Liu,Y. H. Li,et al. Effect of corticosterone on morphine-induced psychomotor effect and its sensitization[C],2004:297-297.
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