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Enhanced mismatch negativity in adolescents with posttraumatic stress disorder (PTSD)
Ge, Yan; Wu, Jianhui; Sun, Xianghong; Zhang, Kan; Zhang, K (reprint author), Chinese Acad Sci, Inst Psychol, State Key Lab Brain & Cognit Sci, 4A Datun Rd, Beijing 100101, Peoples R China.
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摘要The mismatch negativity (MMN) is observed following rare or unique sensory events, and reflects pre-attentional sensory processing of unexpected stimuli. The MMN is altered in several mental illnesses, including post-traumatic stress disorder (PTSD), but did not yield consistent results. We measured MMN in 27 survivors of the Wenchuan earthquake, including 13 who were diagnosed with PTSD, to determine if pre-attentive processing in the auditory cortex was altered by this disease. The amplitude of MMN was significantly greater in the PTSD group compared to the control group. In contrast, no significant group difference was found in the N1 potential, an event-related potential that reflects cortical transmission of sensory information. These results demonstrated an increased sensitivity to deviant stimuli in PTSD that may reflect a chronic state of hyperarousal and hypervigilance in trauma victims. (C) 2010 Published by Elsevier B.V.
关键词Posttraumatic stress disorder Pre-attentive processing Event-related potentials MMN
学科领域Trauma Psychology
2011-02-01
语种英语
发表期刊INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY
ISSN0167-8760
卷号79期号:2页码:231-235
期刊论文类型Article
收录类别SSCI
资助项目三室张侃课题组
项目简介This work was supported by NSF China (90924017) and the Project for Young Scientist Fund, IP, CAS (O9CX062006). We express great appreciation to the teachers and students in Beichuan Vocational High School for their courage after experiencing the earthquake and their supports in this study.
WOS记录号WOS:000288294700017
资助机构NSF China [90924017] ; CAS [O9CX062006]
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被引频次:42[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符https://ir.psych.ac.cn/handle/311026/6991
专题脑与认知科学国家重点实验室
通讯作者Zhang, K (reprint author), Chinese Acad Sci, Inst Psychol, State Key Lab Brain & Cognit Sci, 4A Datun Rd, Beijing 100101, Peoples R China.
作者单位Chinese Acad Sci, Inst Psychol, State Key Lab Brain & Cognit Sci, Beijing 100101, Peoples R China
第一作者单位脑与认知科学国家重点实验室
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Ge, Yan,Wu, Jianhui,Sun, Xianghong,et al. Enhanced mismatch negativity in adolescents with posttraumatic stress disorder (PTSD)[J]. INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY,2011,79(2):231-235.
APA Ge, Yan,Wu, Jianhui,Sun, Xianghong,Zhang, Kan,&Zhang, K .(2011).Enhanced mismatch negativity in adolescents with posttraumatic stress disorder (PTSD).INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY,79(2),231-235.
MLA Ge, Yan,et al."Enhanced mismatch negativity in adolescents with posttraumatic stress disorder (PTSD)".INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY 79.2(2011):231-235.
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