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Enhanced mismatch negativity in adolescents with posttraumatic stress disorder (PTSD)
Ge, Yan; Wu, Jianhui; Sun, Xianghong; Zhang, Kan; Zhang, K (reprint author), Chinese Acad Sci, Inst Psychol, State Key Lab Brain & Cognit Sci, 4A Datun Rd, Beijing 100101, Peoples R China.
2011-02-01
发表期刊INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY
ISSN0167-8760
文章类型Article
卷号79期号:2页码:231-235
产权排序1
摘要The mismatch negativity (MMN) is observed following rare or unique sensory events, and reflects pre-attentional sensory processing of unexpected stimuli. The MMN is altered in several mental illnesses, including post-traumatic stress disorder (PTSD), but did not yield consistent results. We measured MMN in 27 survivors of the Wenchuan earthquake, including 13 who were diagnosed with PTSD, to determine if pre-attentive processing in the auditory cortex was altered by this disease. The amplitude of MMN was significantly greater in the PTSD group compared to the control group. In contrast, no significant group difference was found in the N1 potential, an event-related potential that reflects cortical transmission of sensory information. These results demonstrated an increased sensitivity to deviant stimuli in PTSD that may reflect a chronic state of hyperarousal and hypervigilance in trauma victims. (C) 2010 Published by Elsevier B.V.
关键词Posttraumatic stress disorder Pre-attentive processing Event-related potentials MMN
学科领域Trauma Psychology
收录类别SSCI
语种英语
项目资助者NSF China [90924017] ; CAS [O9CX062006]
资助项目三室张侃课题组
项目简介This work was supported by NSF China (90924017) and the Project for Young Scientist Fund, IP, CAS (O9CX062006). We express great appreciation to the teachers and students in Beichuan Vocational High School for their courage after experiencing the earthquake and their supports in this study.
WOS记录号WOS:000288294700017
引用统计
文献类型期刊论文
条目标识符http://ir.psych.ac.cn/handle/311026/6991
专题脑与认知科学国家重点实验室
通讯作者Zhang, K (reprint author), Chinese Acad Sci, Inst Psychol, State Key Lab Brain & Cognit Sci, 4A Datun Rd, Beijing 100101, Peoples R China.
作者单位Chinese Acad Sci, Inst Psychol, State Key Lab Brain & Cognit Sci, Beijing 100101, Peoples R China
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Ge, Yan,Wu, Jianhui,Sun, Xianghong,et al. Enhanced mismatch negativity in adolescents with posttraumatic stress disorder (PTSD)[J]. INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY,2011,79(2):231-235.
APA Ge, Yan,Wu, Jianhui,Sun, Xianghong,Zhang, Kan,&Zhang, K .(2011).Enhanced mismatch negativity in adolescents with posttraumatic stress disorder (PTSD).INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY,79(2),231-235.
MLA Ge, Yan,et al."Enhanced mismatch negativity in adolescents with posttraumatic stress disorder (PTSD)".INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY 79.2(2011):231-235.
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