MagicViewer: integrated solution for next-generation sequencing data visualization and genetic variation detection and annotation.
Hou HB; Zhao FQ; Zhou LL; Zhu EL; Teng HJ; Li XK; Bao QY; Wu JY; Sun ZS(孙中生); Jinyu Wu
2010
发表期刊Nucleic Acids Research
ISSN0305-1048
卷号38期号:5页码:W732–W736
摘要New sequencing technologies, such as Roche 454, ABI SOLiD and Illumina, have been increasingly developed at an astounding pace with the advantages of high throughput, reduced time and cost. To satisfy the impending need for deciphering the large-scale data generated from next-generation sequencing, an integrated software MagicViewer is developed to easily visualize short read mapping, identify and annotate genetic variation based on the reference genome. MagicViewer provides a user-friendly environment in which large-scale short reads can be displayed in a zoomable interface under user-defined color scheme through an operating system-independent manner. Meanwhile, it also holds a versatile computational pipeline for genetic variation detection, filtration, annotation and visualization, providing details of search option, functional classification, subset selection, sequence association and primer design. In conclusion, MagicViewer is a sophisticated assembly visualization and genetic variation annotation tool for next-generation sequencing data, which can be widely used in a variety of sequencing-based researches, including genome re-sequencing and transcriptome studies. MagicViewer is freely available at http://bioinformatics.zj.cn/magicviewer/.
学科领域生理心理学/生物心理学
收录类别SCI
语种英语
资助项目一室原孙中生课题组
文献类型期刊论文
条目标识符http://ir.psych.ac.cn/handle/311026/7247
专题中国科学院心理研究所回溯数据库(1956-2010)
通讯作者Sun ZS(孙中生); Jinyu Wu
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GB/T 7714
Hou HB,Zhao FQ,Zhou LL,et al. MagicViewer: integrated solution for next-generation sequencing data visualization and genetic variation detection and annotation.[J]. Nucleic Acids Research,2010,38(5):W732–W736.
APA Hou HB.,Zhao FQ.,Zhou LL.,Zhu EL.,Teng HJ.,...&Jinyu Wu.(2010).MagicViewer: integrated solution for next-generation sequencing data visualization and genetic variation detection and annotation..Nucleic Acids Research,38(5),W732–W736.
MLA Hou HB,et al."MagicViewer: integrated solution for next-generation sequencing data visualization and genetic variation detection and annotation.".Nucleic Acids Research 38.5(2010):W732–W736.
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