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Effect of Toll-like receptor 4 on depressive-like behaviors induced by chronic social defeat stress 期刊论文
BRAIN AND BEHAVIOR, 2020, 页码: 10
Authors:  Zhang, Ke;  Lin, Wenjuan;  Zhang, Juntao;  Zhao, Yawei;  Wang, Xiaqing;  Zhao, Mei
Adobe PDF(904Kb)  |  Favorite  |  View/Download:41/0  |  Submit date:2020/02/29
behavioral despair  chronic social defeat stress  depression  inflammation  TLR4  
Transient upregulation of immune activity induced by adolescent social stress is involved in cognitive deficit in adult male mice and early intervention with minocycline 期刊论文
BEHAVIOURAL BRAIN RESEARCH, 2019, 卷号: 374, 页码: 7
Authors:  Zhang, Yu;  Xu, Hang;  Wang, Jiesi;  Ren, Fengyan;  Shao, Feng;  Ellenbroek, Bart;  Lin, Wenjuan;  Wang, Weiwen
Favorite  |  View/Download:22/0  |  Submit date:2020/05/18
Adolescent social stress  Medial prefrontal cortex (mPFC)  Microglia  Tumor necrosis factor alpha (TNF alpha)  Cognitive flexibility  
Fibroblast Growth Factor 2 Modulates Hippocampal Microglia Activation in a Neuroinflammation Induced Model of Depression 期刊论文
FRONTIERS IN CELLULAR NEUROSCIENCE, 2018, 卷号: 12, 页码: 14
Authors:  Tang, Ming-ming;  Lin, Wen-juan;  Pan, Yu-qin;  Li, Ying-cong
Adobe PDF(4947Kb)  |  Favorite  |  View/Download:70/1  |  Submit date:2018/09/10
Fibroblast Growth Factor 2  Microglia  Depressive-like Behavior  Neuroinflammation  Cytokines  Cx3cl1  Hippocampus  
Blocking p38 Signaling Reduces the Activation of Pro-inflammatory Cytokines and the Phosphorylation of p38 in the Habenula and Reverses Depressive-Like Behaviors Induced by Neuroinflammation 期刊论文
FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9, 页码: 1-14
Authors:  Zhao, Ya-wei;  Pan, Yu-qin;  Tang, Ming-ming;  Lin, Wen-juan
Adobe PDF(3912Kb)  |  Favorite  |  View/Download:63/1  |  Submit date:2018/07/02
depression  p38  neuroinflammation  habenula  fluoxetine  SB203580  
抑郁症研究和治疗的新靶标:JNK信号通路的作用 期刊论文
科学通报, 2018, 卷号: 63, 期号: 20, 页码: 1998 ~ 2009
Authors:  张军涛;  林文娟
Adobe PDF(2945Kb)  |  Favorite  |  View/Download:100/1  |  Submit date:2018/10/26
抑郁症  C-jun氨基端激酶  神经萎缩  神经发生  突触可塑性  神经炎症  兴奋性毒性  糖皮质激素抵抗  
Exogenous FGF2 reverses depressive-like behaviors and restores the suppressed FGF2-ERK1/2 signaling and the impaired hippocampal neurogenesis induced by neuroinflammation 期刊论文
BRAIN BEHAVIOR AND IMMUNITY, 2017, 卷号: 66, 期号: 0, 页码: 322-331
Authors:  Tang, Ming-ming;  Lin, Wen-juan;  Zhang, Jun-tao;  Zhao, Ya-wei;  Li, Ying-cong
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Neuroinflammation  Depressive-like behavior  Neurogenesis  Fibroblast growth factor 2  Extracellular signal-regulated kinase 1/2  
中枢免疫失衡与认知功能障碍:聚焦TNFα的作用 期刊论文
心理科学进展, 2017, 卷号: 25, 期号: 12, 页码: 2036–2042
Authors:  张瑜;  林文娟;  王玮文
Adobe PDF(445Kb)  |  Favorite  |  View/Download:105/1  |  Submit date:2017/11/30
内稳态  TNFα  应激  突触可塑性  认知功能  
Hippocampal neurogenesis dysfunction linked to depressive-like behaviors in a neuroinflammation induced model of depression 期刊论文
PHYSIOLOGY & BEHAVIOR, 2016, 卷号: 161, 期号: 0, 页码: 166-173
Authors:  Tang, Ming-ming;  Lin, Wen-juan;  Pan, Yu-qin;  Guan, Xi-ting;  Li, Ying-cong
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Depressive-like Behavior  Neuroinflammation  Neurogenesis  Pro-inflammatory Cytokine  Lipopolysaccharide  
抗炎性细胞因子与抑郁症 期刊论文
生物化学与生物物理进展, 2014, 期号: 11, 页码: 1099-1108
Authors:  徐说;  林文娟
Adobe PDF(533Kb)  |  Favorite  |  View/Download:153/0  |  Submit date:2015/12/02
抑郁症  细胞因子  抗炎性细胞因子  抗炎作用  抗抑郁药  
一个中枢炎性免疫诱发长时程抑郁样行为的新模型 期刊论文
心理学报, 2014, 期号: 5, 页码: 639-646
Authors:  汤明明;  潘玉芹;  林文娟
Adobe PDF(625Kb)  |  Favorite  |  View/Download:134/0  |  Submit date:2015/12/02
抑郁样行为  脂多糖  中枢炎性免疫  时程效应