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D-ribose is elevated in T1DM patients and can be involved in the onset of encephalopathy 期刊论文
AGING-US, 2019, 卷号: 11, 期号: 14, 页码: 4943-4969
Authors:  Yu, Lexiang;  Chen, Yao;  Xu, Yong;  He, Tao;  Wei, Yan;  He, Rongqiao
Adobe PDF(3780Kb)  |  Favorite  |  View/Download:57/0  |  Submit date:2019/10/25
D-ribose  benfotiamine (BTMP)  cognitive impairment  type 1 diabetic encephalopathy  type 1 diabetes mellitus (T1DM)  diabetic encephalopathy  
Ribosylation-Derived Advanced Glycation End Products Induce Tau Hyperphosphorylation Through Brain-Derived Neurotrophic Factor Reduction 期刊论文
JOURNAL OF ALZHEIMERS DISEASE, 2019, 卷号: 71, 期号: 1, 页码: 291-305
Authors:  Wu, Beibei;  Wang, Yujing;  Shi, Chenggang;  Chen, Yao;  Yu, Lexiang;  Li, Juan;  Li, Weiwei;  Wei, Yan;  He, Rongqiao
Favorite  |  View/Download:64/0  |  Submit date:2019/10/25
Advanced glycation end products  brain-derived neurotrophic factor  GSK-3 beta oxidative stress  ribosylation  tau hyperphosphorylation  
D-Ribose as a Contributor to Glycated Haemoglobin 期刊论文
EBIOMEDICINE, 2017, 卷号: 25, 期号: 不详, 页码: 143-153
Authors:  Chen, Xixi;  Su, Tao;  Chen, Yao;  He, Yingge;  Liu, Ying;  Xu, Yong;  Wei, Yan;  Li, Juan;  He, Rongqiao;  Y.Wei;  R. He
Adobe PDF(1419Kb)  |  Favorite  |  View/Download:69/0  |  Submit date:2018/05/04
D-ribose  HbA1c  Type 2 diabetes mellitus  Transketolase  Benfotiamine  
Ribosylation triggering Alzheimer's disease-like Tau hyperphosphorylation via activation of CaMKII 期刊论文
AGING CELL, 2015, 卷号: 14, 期号: 5, 页码: 754-763
Authors:  Wei, Yan;  Han, Chanshuai;  Wang, Yujing;  Wu, Beibei;  Su, Tao;  Liu, Ying;  He, Rongqiao
Adobe PDF(2046Kb)  |  Favorite  |  View/Download:56/6  |  Submit date:2015/12/07
hyperphosphorylation  ribosylation  Tau protein  
Autofluorescence of MDA-modified proteins as an in vitro and in vivo probe in oxidative stress analysis 期刊论文
PROTEIN & CELL, 2014, 卷号: 5, 期号: 6, 页码: 484-487
Authors:  Qiang, Min;  Xu, Yajie;  Lu, Yang;  He, Yingge;  Han, Chanshuai;  Liu, Ying;  He, Rongqiao
Adobe PDF(1145Kb)  |  Favorite  |  View/Download:62/8  |  Submit date:2015/09/09
D-ribosylation induces cognitive impairment through RAGE-dependent astrocytic inflammation 期刊论文
CELL DEATH & DISEASE, 2014, 卷号: 5, 期号: 0, 页码: e1117
Authors:  Han, C.;  Lu, Y.;  Wei, Y.;  Wu, B.;  Liu, Y.;  He, R.
Adobe PDF(4849Kb)  |  Favorite  |  View/Download:51/7  |  Submit date:2015/09/09
advanced glycation end products  astrocyte activation  D-ribose  inflammatory response  RAGE  type 2 diabetes mellitus  
d-Ribosylated Tau forms globular aggregates with high cytotoxicity 期刊论文
CELLULAR AND MOLECULAR LIFE SCIENCES, 2009, 卷号: 66, 期号: 15, 页码: 2559-2571
Authors:  Chen, Lan;  Wei, Yan;  Wang, Xueqing;  He, Rongqiao;  R. Q. He
Adobe PDF(685Kb)  |  Favorite  |  View/Download:214/8  |  Submit date:2011/08/22
D-Ribose  Tau protein  Glycation  Aggregation  Cytotoxicity