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mPFC GABAergic transmission mediated the role of BDNF signaling in cognitive impairment but not anxiety induced by adolescent social stress 期刊论文
NEUROPHARMACOLOGY, 2021, 卷号: 184, 页码: 10
Authors:  Xu, Hang;  Wang, Jiesi;  Jing, Haiyang;  Ellenbroek, Bart;  Shao, Feng;  Wang, Weiwen
Adobe PDF(6687Kb)  |  Favorite  |  View/Download:8/0  |  Submit date:2021/03/29
Adolescent social stress  Depression  Cognitive dysfunction  Anxiety  Brain-derived neurotrophic factor (BDNF)  GABAergic transmission  
Transient upregulation of immune activity induced by adolescent social stress is involved in cognitive deficit in adult male mice and early intervention with minocycline 期刊论文
BEHAVIOURAL BRAIN RESEARCH, 2019, 卷号: 374, 页码: 7
Authors:  Zhang, Yu;  Xu, Hang;  Wang, Jiesi;  Ren, Fengyan;  Shao, Feng;  Ellenbroek, Bart;  Lin, Wenjuan;  Wang, Weiwen
Favorite  |  View/Download:29/0  |  Submit date:2020/05/18
Adolescent social stress  Medial prefrontal cortex (mPFC)  Microglia  Tumor necrosis factor alpha (TNF alpha)  Cognitive flexibility  
Deficiencies of microglia and TNF alpha in the mPFC-mediated cognitive inflexibility induced by social stress during adolescence 期刊论文
BRAIN BEHAVIOR AND IMMUNITY, 2019, 卷号: 79, 页码: 256-266
Authors:  Zhang, Yu;  Xu, Hang;  Zhang, Fan;  Shao, Feng;  Ellenbroek, Bart;  Wang, Jiesi;  Wang, Weiwen
Adobe PDF(2176Kb)  |  Favorite  |  View/Download:114/1  |  Submit date:2019/08/19
Adolescent social stress  Medial prefrontal cortex (mPFC)  Microglia  Tumor necrosis factor alpha (TNF alpha)  Set-shifting  
Chronic clozapine treatment improves the alterations of prepulse inhibition and BDNF mRNA expression in the medial prefrontal cortex that are induced by adolescent social isolation 期刊论文
BEHAVIOURAL PHARMACOLOGY, 2019, 页码: 9
Authors:  Man Li;  Weiwen Wang;  Lan Sun;  Wei Du;  Hao Zhou;  Feng Shao
Adobe PDF(303Kb)  |  Favorite  |  View/Download:6/0  |  Submit date:2021/01/27
adolescent social isolation  brain-derived neurotrophic factor  clozapine  prepulse inhibition  reversal learning  
An Improved Model of Physical and Emotional Social Defeat: Different Effects on Social Behavior and Body Weight of Adolescent Mice by Interaction With Social Support 期刊论文
FRONTIERS IN PSYCHIATRY, 2018, 卷号: 9, 页码: 8
Authors:  Li, Man;  Xu, Hang;  Wang, Weiwen
Adobe PDF(938Kb)  |  Favorite  |  View/Download:114/0  |  Submit date:2019/01/22
Adolescent  Physical Stress  Emotional Stress  Social Behavior  Social Support  
Transcriptomic analysis reveals oxidative phosphorylation activation in an adolescent social isolation rat model 期刊论文
BRAIN RESEARCH BULLETIN, 2018, 卷号: 142, 页码: 304-312
Authors:  Sun, Lan;  Min, Li;  Li, Man;  Shao, Feng;  Wang, Weiwen
Adobe PDF(1697Kb)  |  Favorite  |  View/Download:86/0  |  Submit date:2018/12/04
Schizophrenia  Transcriptomic Analysis  Adolescent Social Isolation  Prefrontal Cortex (Pfc)  Oxidative Phosphorylation (Oxphos)  Comorbidity  
Effects of adolescent social stress and antidepressant treatment on cognitive inflexibility and Bdnf epigenetic modifications in the mPFC of adult mice 期刊论文
PSYCHONEUROENDOCRINOLOGY, 2018, 卷号: 88, 页码: 92-101
Authors:  Xu, Hang;  Wang, Jiesi;  Zhang, Ke;  Zhao, Mei;  Ellenbroek, Bart;  Shao, Feng;  Wang, Weiwen;  F. Shao;  W. Wang
Adobe PDF(968Kb)  |  Favorite  |  View/Download:76/1  |  Submit date:2018/05/28
Adolescent  Social stress  Cognitive inflexibility  Brain-derived neurotrophic factor (BDNF)  Epigenetic mechanism  
Adolescent social isolation affects schizophrenia-like behavior and astrocyte biomarkers in the PFC of adult rats 期刊论文
BEHAVIOURAL BRAIN RESEARCH, 2017, 卷号: 333, 期号: 0, 页码: 258-266
Authors:  Sun, Lan;  Min, Li;  Zhou, Hao;  Li, Man;  Shao, Feng;  Wang, Weiwen;  F. Shao;  W. Wang
Adobe PDF(913Kb)  |  Favorite  |  View/Download:113/1  |  Submit date:2017/11/22
Schizophrenia  Adolescent social isolation  PPI  Prefrontal cortex  Proteomic analysis  Astrocyte development  
Effects of Duloxetine Treatment on Cognitive Flexibility and BDNF Expression in the mPFC of Adult Male Mice Exposed to Social Stress during Adolescence 期刊论文
FRONTIERS IN MOLECULAR NEUROSCIENCE, 2016, 卷号: 9
Authors:  Xu, Hang;  Zhang, Yu;  Zhang, Fan;  Yuan, San-na;  Shao, Feng;  Wang, Weiwen
Adobe PDF(1665Kb)  |  Favorite  |  View/Download:76/0  |  Submit date:2016/11/14
social stress  adolescent  cognitive flexibility  medial prefrontal cortex (mPFC)  brain-derived neurotrophic factor (BDNF)  
Adolescent Social Defeat Induced Alterations in Social Behavior and Cognitive Flexibility in Adult Mice: Effects of Developmental Stage and Social Condition 期刊论文
FRONTIERS IN BEHAVIORAL NEUROSCIENCE, 2016, 卷号: 10, 期号: 0, 页码: 1-11
Authors:  Zhang, Fan;  Yuan, Sanna;  Shao, Feng;  Wang, Weiwen;  Weiwen Wang
Adobe PDF(1227Kb)  |  Favorite  |  View/Download:58/0  |  Submit date:2016/09/05
social defeat stress  adolescent  social condition  social avoidance  cognitive flexibility