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mPFC GABAergic transmission mediated the role of BDNF signaling in cognitive impairment but not anxiety induced by adolescent social stress 期刊论文
NEUROPHARMACOLOGY, 2021, 卷号: 184, 页码: 10
Authors:  Xu, Hang;  Wang, Jiesi;  Jing, Haiyang;  Ellenbroek, Bart;  Shao, Feng;  Wang, Weiwen
Adobe PDF(6687Kb)  |  Favorite  |  View/Download:11/0  |  Submit date:2021/03/29
Adolescent social stress  Depression  Cognitive dysfunction  Anxiety  Brain-derived neurotrophic factor (BDNF)  GABAergic transmission  
The Role of Microglial CX3CR1 in Schizophrenia-Related Behaviors Induced by Social Isolation 期刊论文
FRONTIERS IN INTEGRATIVE NEUROSCIENCE, 2020, 卷号: 14, 页码: 8
Authors:  Zhou, Hao;  Wang, Jiesi;  Zhang, Yu;  Shao, Feng;  Wang, Weiwen
Adobe PDF(1249Kb)  |  Favorite  |  View/Download:22/0  |  Submit date:2020/11/30
CX3CR1  microglia  schizophrenia  social isolation  prepulse inhibition  
Transient upregulation of immune activity induced by adolescent social stress is involved in cognitive deficit in adult male mice and early intervention with minocycline 期刊论文
BEHAVIOURAL BRAIN RESEARCH, 2019, 卷号: 374, 页码: 7
Authors:  Zhang, Yu;  Xu, Hang;  Wang, Jiesi;  Ren, Fengyan;  Shao, Feng;  Ellenbroek, Bart;  Lin, Wenjuan;  Wang, Weiwen
Favorite  |  View/Download:44/0  |  Submit date:2020/05/18
Adolescent social stress  Medial prefrontal cortex (mPFC)  Microglia  Tumor necrosis factor alpha (TNF alpha)  Cognitive flexibility  
Deficiencies of microglia and TNF alpha in the mPFC-mediated cognitive inflexibility induced by social stress during adolescence 期刊论文
BRAIN BEHAVIOR AND IMMUNITY, 2019, 卷号: 79, 页码: 256-266
Authors:  Zhang, Yu;  Xu, Hang;  Zhang, Fan;  Shao, Feng;  Ellenbroek, Bart;  Wang, Jiesi;  Wang, Weiwen
Adobe PDF(2176Kb)  |  Favorite  |  View/Download:128/1  |  Submit date:2019/08/19
Adolescent social stress  Medial prefrontal cortex (mPFC)  Microglia  Tumor necrosis factor alpha (TNF alpha)  Set-shifting  
小胶质细胞与精神疾病相关认知功能障碍 会议论文
第二十二届全国心理学学术会议论文集, 杭州, 2019-10-18
Authors:  王玮文;  邵枫
Favorite  |  View/Download:0/0  |  Submit date:2021/06/01
认知功能障碍  小胶质细胞  早期应激  免疫调节  
社会击败应激诱导的认知功能和前额叶皮质ERK1/2信号通路的脑区依赖性改变 会议论文
摘要集-第二十一届全国心理学学术会议, 北京, 10.30-11.2
Authors:  王琼;  胡伟;  邵枫;  王玮文
Favorite  |  View/Download:126/0  |  Submit date:2018/11/08
社会击败应激  认知灵活性  前额叶皮质  胞外信号调节激酶(erk)  脑源性神经营养因子(bdnf)  
Transcriptomic analysis reveals oxidative phosphorylation activation in an adolescent social isolation rat model 期刊论文
BRAIN RESEARCH BULLETIN, 2018, 卷号: 142, 页码: 304-312
Authors:  Sun, Lan;  Min, Li;  Li, Man;  Shao, Feng;  Wang, Weiwen
Adobe PDF(1697Kb)  |  Favorite  |  View/Download:97/0  |  Submit date:2018/12/04
Schizophrenia  Transcriptomic Analysis  Adolescent Social Isolation  Prefrontal Cortex (Pfc)  Oxidative Phosphorylation (Oxphos)  Comorbidity  
Effects of adolescent social stress and antidepressant treatment on cognitive inflexibility and Bdnf epigenetic modifications in the mPFC of adult mice 期刊论文
PSYCHONEUROENDOCRINOLOGY, 2018, 卷号: 88, 页码: 92-101
Authors:  Xu, Hang;  Wang, Jiesi;  Zhang, Ke;  Zhao, Mei;  Ellenbroek, Bart;  Shao, Feng;  Wang, Weiwen;  F. Shao;  W. Wang
Adobe PDF(968Kb)  |  Favorite  |  View/Download:84/1  |  Submit date:2018/05/28
Adolescent  Social stress  Cognitive inflexibility  Brain-derived neurotrophic factor (BDNF)  Epigenetic mechanism  
Region-Dependent Alterations in Cognitive Function and ERK1/2 Signaling in the PFC in Rats after Social Defeat Stress 期刊论文
NEURAL PLASTICITY, 2018, 页码: 1-12
Authors:  Wang, Qiong;  Shao, Feng;  Wang, Weiwen
Adobe PDF(1977Kb)  |  Favorite  |  View/Download:116/0  |  Submit date:2018/07/02
Adolescent social isolation affects schizophrenia-like behavior and astrocyte biomarkers in the PFC of adult rats 期刊论文
BEHAVIOURAL BRAIN RESEARCH, 2017, 卷号: 333, 期号: 0, 页码: 258-266
Authors:  Sun, Lan;  Min, Li;  Zhou, Hao;  Li, Man;  Shao, Feng;  Wang, Weiwen;  F. Shao;  W. Wang
Adobe PDF(913Kb)  |  Favorite  |  View/Download:123/1  |  Submit date:2017/11/22
Schizophrenia  Adolescent social isolation  PPI  Prefrontal cortex  Proteomic analysis  Astrocyte development