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Disrupted hemispheric connectivity specialization in patients with major depressive disorder: Evidence from the REST-meta-MDD Project 期刊论文
JOURNAL OF AFFECTIVE DISORDERS, 2021, 卷号: 284, 页码: 217-228
Authors:  Ding, Yu-Dan;  Yang, Ru;  Yan, Chao-Gan;  Chen, Xiao;  Bai, Tong-Jian;  Bo, Qi-Jing;  Chen, Guan-Mao;  Chen, Ning-Xuan;  Chen, Tao-Lin;  Chen, Wei;  Cheng, Chang;  Cheng, Yu-Qi;  Cui, Xi-Long;  Duan, Jia;  Fang, Yi-Ru;  Gong, Qi-Yong;  Hou, Zheng-Hua;  Hu, Lan;  Kuang, Li;  Li, Feng;  Li, Tao;  Liu, Yan-Song;  Liu, Zhe-Ning;  Long, Yi-Cheng;  Luo, Qing-Hua;  Meng, Hua-Qing;  Peng, Dai-Hui;  Qiu, Hai-Tang;  Qiu, Jiang;  Shen, Yue-Di;  Shi, Yu-Shu;  Tang, Yanqing;  Wang, Chuan-Yue;  Wang, Fei;  Wang, Kai;  Wang, Li;  Wang, Xiang;  Wang, Ying;  Wu, Xiao-Ping;  Wu, Xin-Ran;  Xie, Chun-Ming;  Xie, Guang-Rong;  Xie, Hai-Yan;  Xie, Peng;  Xu, Xiu-Feng;  Yang, Hong;  Yang, Jian;  Yao, Jia-Shu;  Yao, Shu-Qiao;  Yin, Ying-Ying;  Yuan, Yong-Gui;  Zhang, Ai-Xia;  Zhang, Hong;  Zhang, Ke-Rang;  Zhang, Lei;  Zhang, Zhi-Jun;  Zhou, Ru-Bai;  Zhou, Yi-Ting;  Zhu, Jun-Juan;  Zou, Chao-Jie;  Si, Tian-Mei;  Zang, Yu-Feng;  Zhao, Jing-Ping;  Guo, Wen-Bin
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Major depressive disorder  hemispheric asymmetry  parameter of asymmetry  fMRI Abbreviations ACC, Anterior cingulate gyrus  DLPFC, Dorsolateral prefrontal cortex  DMN, Default mode network  DPARSF, Data Processing Assistant for Resting-State fMRI  DSM, Diagnosic and Statistical Manual of Mental Disorders  EEG, Electroencephalographic  FC, Functional connectivity  FDR, False discovery rate  FEDN, First-episode, drug-naive  FEF, Frontal eye fields  fMRI, Functional magnetic resonance imaging  HAMD, Hamilton Depression Rating Scale  HC, Healthy control  IFG, Inferior frontal gyrus  IPL, Inferior parietal lobule  IPS/SPL, Intraparietal sulcus/superior parietal lobule  LMM, Linear mixed model  MDD, Major depressive disorder  MFG, Middle frontal gyrus  MTG, Middle temporal gyrus  PAS, Parameter of asymmetry  PCC, Posterior cingulate cortex  PET, Positron emission tomography  ROIs, Regions of interest  rs-fMRI, Resting-state fMRI  rTMS, repetitive transcranial magnetic stimulation  STS, Superior temporal sulcus  VMHC, Voxel-mirrored homotopic connectivity  
Inhibition of JNK ameliorates depressive-like behaviors and reduces the activation of pro-inflammatory cytokines and the phosphorylation of glucocorticoid receptors at serine 246 induced by neuroinflammation 期刊论文
PSYCHONEUROENDOCRINOLOGY, 2020, 卷号: 113, 页码: 10
Authors:  Zhang, Juntao;  Lin, Wenjuan;  Tang, Mingming;  Zhao, Yawei;  Zhang, Ke;  Wang, Xiaqing;  Li, Yingcong
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Neuroinflammation  Depressive-like behavior  JNK  Proinflammatory cytokines  Glucocorticoid receptor  
Effect of Toll-like receptor 4 on depressive-like behaviors induced by chronic social defeat stress 期刊论文
BRAIN AND BEHAVIOR, 2020, 页码: 10
Authors:  Zhang, Ke;  Lin, Wenjuan;  Zhang, Juntao;  Zhao, Yawei;  Wang, Xiaqing;  Zhao, Mei
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behavioral despair  chronic social defeat stress  depression  inflammation  TLR4  
Transient upregulation of immune activity induced by adolescent social stress is involved in cognitive deficit in adult male mice and early intervention with minocycline 期刊论文
BEHAVIOURAL BRAIN RESEARCH, 2019, 卷号: 374, 页码: 7
Authors:  Zhang, Yu;  Xu, Hang;  Wang, Jiesi;  Ren, Fengyan;  Shao, Feng;  Ellenbroek, Bart;  Lin, Wenjuan;  Wang, Weiwen
Favorite  |  View/Download:45/0  |  Submit date:2020/05/18
Adolescent social stress  Medial prefrontal cortex (mPFC)  Microglia  Tumor necrosis factor alpha (TNF alpha)  Cognitive flexibility  
Fibroblast Growth Factor 2 Modulates Hippocampal Microglia Activation in a Neuroinflammation Induced Model of Depression 期刊论文
FRONTIERS IN CELLULAR NEUROSCIENCE, 2018, 卷号: 12, 页码: 14
Authors:  Tang, Ming-ming;  Lin, Wen-juan;  Pan, Yu-qin;  Li, Ying-cong
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Fibroblast Growth Factor 2  Microglia  Depressive-like Behavior  Neuroinflammation  Cytokines  Cx3cl1  Hippocampus  
Blocking p38 Signaling Reduces the Activation of Pro-inflammatory Cytokines and the Phosphorylation of p38 in the Habenula and Reverses Depressive-Like Behaviors Induced by Neuroinflammation 期刊论文
FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9, 页码: 1-14
Authors:  Zhao, Ya-wei;  Pan, Yu-qin;  Tang, Ming-ming;  Lin, Wen-juan
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depression  p38  neuroinflammation  habenula  fluoxetine  SB203580  
抑郁症研究和治疗的新靶标:JNK信号通路的作用 期刊论文
科学通报, 2018, 卷号: 63, 期号: 20, 页码: 1998 ~ 2009
Authors:  张军涛;  林文娟
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抑郁症  C-jun氨基端激酶  神经萎缩  神经发生  突触可塑性  神经炎症  兴奋性毒性  糖皮质激素抵抗  
Exogenous FGF2 reverses depressive-like behaviors and restores the suppressed FGF2-ERK1/2 signaling and the impaired hippocampal neurogenesis induced by neuroinflammation 期刊论文
BRAIN BEHAVIOR AND IMMUNITY, 2017, 卷号: 66, 期号: 0, 页码: 322-331
Authors:  Tang, Ming-ming;  Lin, Wen-juan;  Zhang, Jun-tao;  Zhao, Ya-wei;  Li, Ying-cong
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Neuroinflammation  Depressive-like behavior  Neurogenesis  Fibroblast growth factor 2  Extracellular signal-regulated kinase 1/2  
中枢免疫失衡与认知功能障碍:聚焦TNFα的作用 期刊论文
心理科学进展, 2017, 卷号: 25, 期号: 12, 页码: 2036–2042
Authors:  张瑜;  林文娟;  王玮文
Adobe PDF(445Kb)  |  Favorite  |  View/Download:130/1  |  Submit date:2017/11/30
内稳态  TNFα  应激  突触可塑性  认知功能  
Hippocampal neurogenesis dysfunction linked to depressive-like behaviors in a neuroinflammation induced model of depression 期刊论文
PHYSIOLOGY & BEHAVIOR, 2016, 卷号: 161, 期号: 0, 页码: 166-173
Authors:  Tang, Ming-ming;  Lin, Wen-juan;  Pan, Yu-qin;  Guan, Xi-ting;  Li, Ying-cong
Adobe PDF(1272Kb)  |  Favorite  |  View/Download:132/1  |  Submit date:2016/07/14
Depressive-like Behavior  Neuroinflammation  Neurogenesis  Pro-inflammatory Cytokine  Lipopolysaccharide