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Variants of opioid system genes are associated with non-dependent opioid use and heroin dependence 期刊论文
DRUG AND ALCOHOL DEPENDENCE, 2016, 卷号: 168, 期号: 0, 页码: 164-169
Authors:  Randesi, Matthew;  van den Brink, Wim;  Levran, Orna;  Blanken, Peter;  Butelman, Eduardo R.;  Yuferov, Vadim;  da Rosa, Joel Correa;  Ott, Jurg;  van Ree, Jan M.;  Kreek, Mary Jeanne
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Heroin Addiction  Non-dependent Opioid Use  Heroin-assisted Treatment  Opioid Genes  Rs2236861  
HDR: a statistical two-step approach successfully identifies disease genes in autosomal recessive families 期刊论文
JOURNAL OF HUMAN GENETICS, 2016, 卷号: 61, 期号: 11, 页码: 959-963
Authors:  Imai, Atsuko;  Kohda, Masakazu;  Nakaya, Akihiro;  Sakata, Yasushi;  Murayama, Kei;  Ohtake, Akira;  Lathrop, Mark;  Okazaki, Yasushi;  Ott, Jurg
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African-specific variability in the acetylcholine muscarinic receptor M4: association with cocaine and heroin addiction 期刊论文
PHARMACOGENOMICS, 2016, 卷号: 17, 期号: 9, 页码: 995-1003
Authors:  Levran, Orna;  Randesi, Matthew;  Peles, Einat;  da Rosa, Joel Correa;  Ott, Jurg;  Rotrosen, John;  Adelson, Miriam;  Kreek, Mary Jeanne
Adobe PDF(1018Kb)  |  Favorite  |  View/Download:20/1  |  Submit date:2016/09/05
African Ancestry  Cholinergic Receptors  Chrm4  Cocaine Addiction  Opioid Addiction  
Glutamatergic and GABAergic susceptibility loci for heroin and cocaine addiction in subjects of African and European ancestry 期刊论文
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, 2016, 卷号: 64, 期号: 0, 页码: 118-123
Authors:  Levran, Orna;  Peles, Einat;  Randesi, Matthew;  da Rosa, Joel Correa;  Ott, Jurg;  Rotrosen, John;  Adelson, Miriam;  Kreek, Mary Jeanne
Adobe PDF(355Kb)  |  Favorite  |  View/Download:46/1  |  Submit date:2015/12/07
Addiction  African Americans  Cocaine  GAD1, glutamate, GABA  Heroin  
Synaptic Plasticity and Signal Transduction Gene Polymorphisms and Vulnerability to Drug Addictions in Populations of European or African Ancestry 会议论文
CNS NEUROSCIENCE & THERAPEUTICS, 不详, 不详
Authors:  Levran, O (Levran, Orna);  Peles, E (Peles, Einat);  Randesi, M (Randesi, Matthew);  da Rosa, JC (da Rosa, Joel Correa);  Ott, J (Ott, Jurg);  Rotrosen, J (Rotrosen, John);  Rotrosen, J (Rotrosen, John);  Kreek, MJ (Kreek, Mary Jeanne)
Favorite  |  View/Download:27/0  |  Submit date:2018/08/29
African Americans  Cocaine Addiction  Heroin Addiction  Signal Transduction  Synaptic Plasticity  
Common Regulatory Variants of CYFIP1 Contribute to Susceptibility for Autism Spectrum Disorder (ASD) and Classical Autism 期刊论文
ANNALS OF HUMAN GENETICS, 2015, 卷号: 79, 期号: 5, 页码: 329-340
Authors:  Wang, Jian;  Tao, Yu;  Song, Fan;  Sun, Yue;  Ott, Jurg;  Saffen, David
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CYFIP1  autism spectrum disorder  regulatory genetic variant  expression quantitative locus (eQTL)  
Leveling the Playing Field in Homozygosity Mapping Using Map Distances 期刊论文
ANNALS OF HUMAN GENETICS, 2015, 卷号: 79, 期号: 5, 页码: 366-372
Authors:  Li, Yi;  Cagirici, Halise Busra;  Horpaopan, Sukanya;  Ott, Jurg;  Imai, Atsuko;  Majewski, Jacek;  Lathrop, Mark
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Homozygosity mapping  linkage disequilibrium  recombination  
Beyond Homozygosity Mapping: Family-Control analysis based on Hamming distance for prioritizing variants in exome sequencing 期刊论文
SCIENTIFIC REPORTS, 2015, 卷号: 5, 期号: 0, 页码: 12028
Authors:  Imai, Atsuko;  Nakaya, Akihiro;  Fahiminiya, Somayyeh;  Tetreault, Martine;  Majewski, Jacek;  Sakata, Yasushi;  Takashima, Seiji;  Lathrop, Mark;  Ott, Jurg
Adobe PDF(323Kb)  |  Favorite  |  View/Download:43/3  |  Submit date:2015/09/08
Overlapping Dopaminergic Pathway Genetic Susceptibility to Heroin and Cocaine Addictions in African Americans 期刊论文
ANNALS OF HUMAN GENETICS, 2015, 卷号: 79, 期号: 3, 页码: 188-198
Authors:  Levran, Orna;  Randesi, Matthew;  da Rosa, Joel Correa;  Ott, Jurg;  Rotrosen, John;  Adelson, Miriam;  Kreek, Mary Jeanne
Adobe PDF(427Kb)  |  Favorite  |  View/Download:31/3  |  Submit date:2015/09/10
Dopaminergic pathway  polymorphism  heroin addiction  cocaine addiction  African Americans  DRD1  DRD2  COMT Val158Met  rs5326  rs1075650  rs2283265  
Genetic linkage analysis in the age of whole-genome sequencing 期刊论文
NATURE REVIEWS GENETICS, 2015, 卷号: 16, 期号: 5, 页码: 275-284
Authors:  Ott, Jurg;  Wang, Jing;  Leal, Suzanne M.
Adobe PDF(366Kb)  |  Favorite  |  View/Download:142/69  |  Submit date:2015/09/10