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Alteration of the PKA-CREB cascade in the mPFC accompanying prepulse inhibition deficits: evidence from adolescent social isolation and chronic SKF38393 injection during early adolescence 期刊论文
BEHAVIOURAL PHARMACOLOGY, 2021, 卷号: 32, 期号: 6, 页码: 487-496
Authors:  Du, Wei;  Li, Man;  Zhou, Hao;  Shao, Feng;  Wang, Weiwen
Favorite  |  View/Download:7/0  |  Submit date:2021/09/24
adolescent social isolation  cAMP-dependent protein kinase A  cAMP-response element-binding protein  medial prefrontal cortex  prepulse inhibition  
The Role of Microglial CX3CR1 in Schizophrenia-Related Behaviors Induced by Social Isolation 期刊论文
FRONTIERS IN INTEGRATIVE NEUROSCIENCE, 2020, 卷号: 14, 页码: 8
Authors:  Zhou, Hao;  Wang, Jiesi;  Zhang, Yu;  Shao, Feng;  Wang, Weiwen
Adobe PDF(1249Kb)  |  Favorite  |  View/Download:37/0  |  Submit date:2020/11/30
CX3CR1  microglia  schizophrenia  social isolation  prepulse inhibition  
Enhancement of Aggression Induced by Isolation Rearing is Associated with a Lack of Central Serotonin 期刊论文
NEUROSCIENCE BULLETIN, 2019, 卷号: 35, 期号: 5, 页码: 841-852
Authors:  Liu, Yiqiong;  Sun, Yunong;  Zhao, Xiaoyan;  Kim, Ji-Young;  Luo, Lu;  Wang, Qian;  Meng, Xiaolu;  Li, Yonghui;  Sui, Nan;  Chen, Zhou-Feng;  Pan, Chuxiong;  Li, Liang;  Zhang, Yan
Adobe PDF(1814Kb)  |  Favorite  |  View/Download:116/1  |  Submit date:2019/10/31
5-HT  Aggression  Social isolation  Dopamine  Lmx1b  
Chronic clozapine treatment improves the alterations of prepulse inhibition and BDNF mRNA expression in the medial prefrontal cortex that are induced by adolescent social isolation 期刊论文
BEHAVIOURAL PHARMACOLOGY, 2019, 页码: 9
Authors:  Man Li;  Weiwen Wang;  Lan Sun;  Wei Du;  Hao Zhou;  Feng Shao
Adobe PDF(303Kb)  |  Favorite  |  View/Download:16/0  |  Submit date:2021/01/27
adolescent social isolation  brain-derived neurotrophic factor  clozapine  prepulse inhibition  reversal learning  
Transcriptomic analysis reveals oxidative phosphorylation activation in an adolescent social isolation rat model 期刊论文
BRAIN RESEARCH BULLETIN, 2018, 卷号: 142, 页码: 304-312
Authors:  Sun, Lan;  Min, Li;  Li, Man;  Shao, Feng;  Wang, Weiwen
Adobe PDF(1697Kb)  |  Favorite  |  View/Download:107/0  |  Submit date:2018/12/04
Schizophrenia  Transcriptomic Analysis  Adolescent Social Isolation  Prefrontal Cortex (Pfc)  Oxidative Phosphorylation (Oxphos)  Comorbidity  
Adolescent social isolation affects schizophrenia-like behavior and astrocyte biomarkers in the PFC of adult rats 期刊论文
BEHAVIOURAL BRAIN RESEARCH, 2017, 卷号: 333, 期号: 0, 页码: 258-266
Authors:  Sun, Lan;  Min, Li;  Zhou, Hao;  Li, Man;  Shao, Feng;  Wang, Weiwen;  F. Shao;  W. Wang
Adobe PDF(913Kb)  |  Favorite  |  View/Download:131/1  |  Submit date:2017/11/22
Schizophrenia  Adolescent social isolation  PPI  Prefrontal cortex  Proteomic analysis  Astrocyte development  
Cognitive dysfunction and epigenetic alterations of the BDNF gene are induced by social isolation during early adolescence 期刊论文
BEHAVIOURAL BRAIN RESEARCH, 2016, 卷号: 313, 期号: 0, 页码: 177-183
Authors:  Li, Man;  Du, Wei;  Shao, Feng;  Wang, Weiwen
Adobe PDF(868Kb)  |  Favorite  |  View/Download:91/2  |  Submit date:2016/11/14
Social Isolation  Cognitive Behaviour  Brain-derived Neurotrophic Factor (Bdnf)  Epigenetics  
Cognitive dysfunction and epigenetic alterations at the BDNF gene are induced by social isolation during early adolescence 期刊论文
Behavioural Brain Research, 2016, 卷号: 313, 期号: 不详, 页码: 177-183
Authors:  Man Li;  Wei Du;  Feng Shao;  Weiwen Wang;  F. Shao;  W. Wang
Adobe PDF(868Kb)  |  Favorite  |  View/Download:59/0  |  Submit date:2018/04/27
Social isolation  Cognitive behaviour  Brain-derived neurotrophic factor (BDNF)  Epigenetics  
Galanthamine, an acetylcholine inhibitor, prevents prepulse inhibition deficits induced by adolescent social isolation or MK-801 treatment 期刊论文
BRAIN RESEARCH, 2014, 卷号: 1589, 期号: 1589, 页码: 105-111
Authors:  Shao, Shuang;  Li, Man;  Du, Wei;  Shao, Feng;  Wang, Weiwen
Adobe PDF(683Kb)  |  Favorite  |  View/Download:86/16  |  Submit date:2015/09/18
Adolescence  Mk-801  Social Isolation  Galanthamine  Prepulse Inhibition  
Adolescent social isolation influences cognitive function in adult rats 期刊论文
NEURAL REGENERATION RESEARCH, 2013, 卷号: 8, 期号: 11, 页码: 1025-1030
Authors:  Sheo, Feng;  Han, Xiao;  Sheo, Shuang;  Wang, Weiwen
Adobe PDF(245Kb)  |  Favorite  |  View/Download:91/8  |  Submit date:2015/05/19
neural regeneration  adolescence  social isolation  latent inhibition  brain-derived neurotrophic factor  medial prefrontal cortex  nucleus accumbens  adult  cognitive function  neurodevelopmental disorders  grants-supported paper  neuroregeneration