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| Gender differences in prevalence and clinical risk factors of suicide attempts in young adults with first-episode drug-naive major depressive disorder | |
Zhu, Quanfeng1; Lang, Xiaoe2; Zhang, Xiang-Yang3,4
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| 通讯作者 | Zhang, Xiang-Yang(zhangxy@psych.ac.cn) |
| 摘要 | BackgroundSuicide rates in adolescents with major depressive disorder (MDD) change with age and gender. Early adulthood is an important transitional stage between late adolescence and adulthood, in which an individual's mind gradually matures. However, there are fewer studies on prevalence and variables linked to the suicide attempts of young adults with MDD. AimsTo explore gender differences in the prevalence and risk factors associated with suicide attempts in young adults with first-episode drug-naive MDD. MethodThe Hamilton Rating Scale for Depression (HRSD), Hamilton Rating Scale for Anxiety (HRSA) and Positive Subscale of the Positive and Negative Syndrome Scale (PANSS) were used to assess depression, anxiety and psychotic symptoms respectively and various biochemical indicators were assessed. ResultsAmong 293 young adults with first-episode drug-naive MDD, the prevalence of suicide attempts was 15.45% (19/123) for males and 14.12% (24/170) for females. Males with suicide attempts had higher levels of thyroid-stimulating hormone (TSH) and higher PANSS Positive Subscale scores, whereas females with suicide attempts had higher TSH, serum total cholesterol, fasting blood glucose and diastolic blood pressure levels and higher scores on the HRSD, HRSA, PANSS Positive Subscale (all Bonferroni corrected P < 0.05). In males, PANSS Positive Subscale score (B = 0.17, P = 0.03, OR = 1.19, 95% CI 1.02-1.38) was a risk factor for suicide attempts. ConclusionsThere were significant gender differences in the risk factors for suicide attempts in young adults with first-episode drug-naive MDD. |
| 关键词 | First-episode drug-naive adolescence major depressive disorder suicide attempts |
| 2024-01-05 | |
| 语种 | 英语 |
| DOI | 10.1192/bjo.2023.635 |
| 发表期刊 | BJPSYCH OPEN
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| ISSN | 2056-4724 |
| 卷号 | 10期号:1页码:6 |
| 收录类别 | SCI |
| 出版者 | CAMBRIDGE UNIV PRESS |
| WOS关键词 | MORTALITY ; SYMPTOMS ; IDEATION ; INSIGHT ; GLUCOSE ; WOMEN |
| WOS研究方向 | Psychiatry |
| WOS类目 | Psychiatry |
| WOS记录号 | WOS:001136535100001 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | https://ir.psych.ac.cn/handle/311026/46843 |
| 专题 | 中国科学院心理健康重点实验室 |
| 通讯作者 | Zhang, Xiang-Yang |
| 作者单位 | 1.Hangzhou Normal Univ, Affiliated Xiaoshan Hosp, Hangzhou, Peoples R China 2.Shanxi Med Univ, Hosp 1, Dept Psychiat, Clin Med Coll 1, Taiyuan, Peoples R China 3.Inst Psychol, CAS Key Lab Mental Hlth, Beijing, Peoples R China 4.Univ Chinese Acad Sci, Dept Psychol, Beijing, Peoples R China |
| 通讯作者单位 | 中国科学院心理健康重点实验室 |
| 推荐引用方式 GB/T 7714 | Zhu, Quanfeng,Lang, Xiaoe,Zhang, Xiang-Yang. Gender differences in prevalence and clinical risk factors of suicide attempts in young adults with first-episode drug-naive major depressive disorder[J]. BJPSYCH OPEN,2024,10(1):6. |
| APA | Zhu, Quanfeng,Lang, Xiaoe,&Zhang, Xiang-Yang.(2024).Gender differences in prevalence and clinical risk factors of suicide attempts in young adults with first-episode drug-naive major depressive disorder.BJPSYCH OPEN,10(1),6. |
| MLA | Zhu, Quanfeng,et al."Gender differences in prevalence and clinical risk factors of suicide attempts in young adults with first-episode drug-naive major depressive disorder".BJPSYCH OPEN 10.1(2024):6. |
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| 文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
| Gender differences i（220KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | 浏览 下载 | |
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