|Alternative Title||An intervention study on mental time travel in schizophrenia|
|Place of Conferral||北京|
|Keyword||心理时间之旅 精神分裂症 生命回顾训练 回忆过去 想象未来|
|Abstract||背景：心理时间之旅(mental time travel)是指我们在心理上将自我投射到过去重新经历过去的事情，以及把自我投射到未来，预先经历未来事情的能力。这种能力在人们的日常生活中起着重要的作用。精神分裂症患者心理时间之旅存在缺损，但以往大多数研究集中在对过去事件的回忆上，关于想象未来的研究较少，而且对精神分裂症患者这一缺损的干预研究更少。|
目的：本研究通过对精神分裂症患者进行生命回顾训练(Life Review Therapy)干预，考察能否提高精神分裂症患者回忆过去和想象未来的能力，以及能否改善患者的情绪状态和生活满意度等。
|Other Abstract||Background:Mental Time Travel (MTT) is the ability that individuals project themselves to the past and re-experiencing their past experiences, or project themselves to the future to pre-experience the future. This ability is important in daily lives. Studies have shown that schizophrenia patients were impaired in MTT. To date, most studies of MTT were on remembering the past, only a few studies explored imaging the future, and even less studies examined how to improve MTT in patients with schizophrenia.|
Objective: Our study aimed to examine whether MTT in patients with schizophrenia can be improved through the Life Review Therapy, andemotion state and life satisfaction, etc. can be improved as well.
Methods:This study recruited 50 patients with schizophrenia, they were randomly assigned to the training group (SZ-training) and control group (SZ-control), each group consisted 25 patients. The SZ-control group only accepted conventional anti-psychotic medication treatment. On the other hand, the SZ-training group received the Life Review Therapy in addition to conventional anti-psychotic medication treatment. Life Review Therapy consisted of practices of retrieving autobiographical events from specific time period in one's life. The therapy was divided into four weeks, twice a week, and each training session lasted for about an hour. MTT, self-reported emotional status, life satisfaction and basic cognitive functions were assess before and after training for both groups. The event specificity, field perspective, and category of events that participants remembered or imagined were the main index of MTT. At the same time, we also recruited 25 healthy controls who completed all the assessments at baseline to compare the difference between schizophrenia patients and healthy controls.
Results:Resultofpre-trainingassessmentshowedthatboth SZ groups showed impairments in remembering the pastand imagining the future compared to healthy controls.SZ patients adopted less field perspective than healthy controls in MTT. Of the content of events generated in MTT, SZ patients showed a lower proportion in categories of relationship and entertainment, and higher proportion in categories of hospital-related, non-classifiable, and no response compared to healthy controls.
Results of post-training assessment showed that the specificity of events generated in MTT in SZ-training group was higher than that of SZ-control group, and no significant difference was found between SZ-training group and healthy control group. The field perspective adopted in SZ-training group was higher than that of the SZ-control group, and no significant difference was found between SZ-training group and healthy control group. The proportion of exploring/entertainment events in SZ-training group was higher than SZ-control group, and no significant difference was found between SZ-training group and healthy control group. The proportion of unclassifiable and no response in the SZ-training group was lower than SZ-control group, and no significant difference was found between SZ-training group and healthy control group.
For self-reported assessments, SZ-training group showed significant improvement in emotional expression. There was no significant improvement in depression or anxiety nor increase in life-satisfaction. Significant improvement was found in semantic memory, and verbal fluency in SZ-training group.
Conclusions:Schizophrenia patients showed impairment in remembering the past and imagining the future, and Life Review Therapy is effective in improving the specificity of MTT and made the content more adaptive. It can also improve patients' emotion expression and basic cognitive functions.
|陈桂芳. 精神分裂症心理时间之旅的干预研究[D]. 北京. 中国科学院研究生院,2016.|
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