Brain imaging of a gamified cognitive flexibility task in young and older adults

doi:10.1007/s11682-024-00883-w

PSYCH OpenIR

	Brain imaging of a gamified cognitive flexibility task in young and older adults
	Wang, Ping 1,2,3; Guo, Sheng-Ju 1,2; Li, Hui-Jie 1,2
通讯作者	Li, Hui-Jie(lihj@psych.ac.cn)
摘要	The study aimed to develop and validate a gamified cognitive flexibility task through brain imaging, and to investigate behavioral and brain activation differences between young and older adults during task performance. Thirty-one young adults (aged 18-35) and 31 older adults (aged 60-80) were included in the present study. All participants underwent fMRI scans while completing the gamified cognitive flexibility task. Results showed that young adults outperformed older adults on the task. The left inferior frontal junction (IFJ), a key region of cognitive flexibility, was significantly activated during the task in both older and young adults. Comparatively, the percent signal change in the left IFJ was stronger in older adults than in young adults. Moreover, older adults demonstrated more precise representations during the task in the left IFJ. Additionally, the left inferior parietal lobule (IPL) and superior parietal lobule in older adults and the left middle frontal gyrus (MFG) and inferior frontal gyrus in young adults were also activated during the task. Psychophysiological interaction analyses showed significant functional connectivity between the left IFJ and the left IPL, as well as the right precuneus in older adults. In young adults, significant functional connectivity was found between the left IFJ and the left MFG, as well as the right angular. The current study provides preliminary evidence for the validity of the gamified cognitive flexibility task through brain imaging. The findings suggest that this task could serve as a reliable tool for assessing cognitive flexibility and for exploring age-related differences of cognitive flexibility in both brain and behavior.
关键词	Brain imaging Cognitive flexibility Inferior frontal junction Young adults Older adults
	2024-08-01
语种	英语
DOI	10.1007/s11682-024-00883-w
发表期刊	BRAIN IMAGING AND BEHAVIOR
ISSN	1931-7557
卷号	18 期号:4 页码:902-912
收录类别	SCI
资助项目	China Postdoctoral Science Foundation
出版者	SPRINGER
WOS关键词	AGE-RELATED-CHANGES ; MEMORY ; ACTIVATIONS ; VARIABILITY ; RELIABILITY ; INHIBITION ; NETWORKS ; JUNCTION
WOS研究方向	Neurosciences & Neurology
WOS类目	Neuroimaging
WOS记录号	WOS:001312762600010
资助机构	China Postdoctoral Science Foundation
引用统计
文献类型	期刊论文
条目标识符	https://ir.psych.ac.cn/handle/311026/48987
通讯作者	Li, Hui-Jie
作者单位	1.Chinese Acad Sci, Inst Psychol, CAS Key Lab Behav Sci, 16 Lincui Rd, Beijing 100101, Peoples R China 2.Univ Chinese Acad Sci, Dept Psychol, Beijing 100101, Peoples R China 3.Beijing Normal Univ, McGovern Inst Brain Res, State Key Lab Cognit Neurosci & Learning, Beijing 100875, Peoples R China
推荐引用方式 GB/T 7714	Wang, Ping,Guo, Sheng-Ju,Li, Hui-Jie. Brain imaging of a gamified cognitive flexibility task in young and older adults[J]. BRAIN IMAGING AND BEHAVIOR,2024,18(4):902-912.
APA	Wang, Ping,Guo, Sheng-Ju,&Li, Hui-Jie.(2024).Brain imaging of a gamified cognitive flexibility task in young and older adults.BRAIN IMAGING AND BEHAVIOR,18(4),902-912.
MLA	Wang, Ping,et al."Brain imaging of a gamified cognitive flexibility task in young and older adults".BRAIN IMAGING AND BEHAVIOR 18.4(2024):902-912.