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早期应激对抑郁相关行为及神经内分泌反应的长期影响
Alternative TitleLong-term Effects of Early-life Stress on Behavioral and Neuroendocrine Changes Associated with Depression
王玮文; 邵枫; 刘美; 林文娟
2006
Source Publication心理科学进展
ISSN1671-3710
Volume14Issue:6Pages:907-911
Abstract临床研究发现,早期创伤性经历是导致成年抑郁症易感性增加的高风险因素之一。但早期应激通过何种途径对抑郁发病产生长期的影响,目前尚不清楚。本文综述了近年来有关的实验动物研究,从早期应激的动物模型建立、早期应激对成年动物抑郁相关行为及神经内分泌反应的长期影响等方面进行了系统论述和分析,进而提出了早期应激并不影响动物的本能行为,但早期应激影响与行为动机和应激应对等认知相关的行为的观点,进一步论证了早期应激是通过增加个体潜在的易患病素质对抑郁症发病产生影响。
Keyword早期应激 抑郁 行为 神经内分泌
Subject Area生理心理学/生物心理学 ; 创伤心理学
Indexed By中文核心期刊要目总览 ASPT来源刊 CJFD收录刊
Language中文
Funding Project国家自然科学基金项目资助(批准号:30500158)。
NoteClinical studies indicate early traumatic experiences are high risk factors in the development of depression in adulthood. The pathways that mediate the long-term effects of early-life stress on pathophysiology of depression are still unclear. This article reviewed laboratory animal studies in which the early-life stress models and the stress-induced chronic behavioral and neurobiological changes associated with depression were examined. It is concluded that early-life stress influenced behavior implicated ...
Document Type期刊论文
Identifierhttp://ir.psych.ac.cn/handle/311026/3270
Collection中国科学院心理研究所回溯数据库(1956-2010)
Corresponding Author林文娟
Recommended Citation
GB/T 7714
王玮文,邵枫,刘美,等. 早期应激对抑郁相关行为及神经内分泌反应的长期影响[J]. 心理科学进展,2006,14(6):907-911.
APA 王玮文,邵枫,刘美,&林文娟.(2006).早期应激对抑郁相关行为及神经内分泌反应的长期影响.心理科学进展,14(6),907-911.
MLA 王玮文,et al."早期应激对抑郁相关行为及神经内分泌反应的长期影响".心理科学进展 14.6(2006):907-911.
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