As migration is increasingly prevalent around the world, there is an increasing need to pay attention to the cultural adaptation of the migrants and the relevant influencing factors. Cultural adaptation plays an important role in the health of migrants，The psychological and cultural adaptation characteristics experienced by domestic migrants are the same as those of international migrants. Objective: To examine the validity and reliability of the Acculturation Screening Questionnaire (ASQ) in domestic migrants;Analyze the influence relationship of cultural adaptation wellbeing. Methods: 805 migrants living in Guangzhou were selected (Sample 1)、migrants living in Shenzhen were selected (Sample 2) and 214 migrants living in Shanghai were selected (Sample 3), 805migrants (Sample 1) were used for item analysis and exploratory factor analysis,203 migrants (Sample 2)were used for confirmatory factor analysis and criterion-related validity,214 migrants (Sample 3)were used for internal consistency analysis.103 migrants were selected from sample 3 for retest at an interval of 5 months. The Subject Well Being Scale(SWBS)，Depression Anxiety Stress Scale( DASS )and Loneliness Scale( LS)were used to test the validity of the criterion. Understand the influence relationship between cultural adaptation and happiness of migrants. Results: 9 common factors were extracted by exploratory factor analysis, a total of 114 items. Confirmatory factor analysis indicated that the factor model fitting was good. The scores of life anxiety, homesickness, and happiness of ASQ were positively correlated with the scores of DASS、SWBS and LS. The Cronbach a coefficient and test-retest reliability of the ASQ 9 factors meet the measurement index requirements. T test domestic migrants have significant differences in Residence status, Overall distress compared with Shanghai people. Both the cultural adaptation and wellbeing showed a positive correlation. Regression analysis the Homesickness、Life anxiety and Wellbeing as dependent variables, Comfortable family relationships and Comfortable social relationships got higher score. Conclusion: The Chinese version of the Acculturation Screening Questionnaire shows good validity and reliability among domestic migrants. Domestic migrants in Residence Status, Overall Distress experience higher psychological anxiety than local people. There was a significant positive correlation between the cultural adaptation with Wellbeing. Comfortable family relationships and Comfortable social relationships have proved to be the most important influencing factors of the Well-being of acculturative result.
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