其他摘要 | Cervical cancer ranks second in the global incidence of female cancer and is one of the common malignant tumors that threaten women's health. Fortunately, cervical cancer is a special kind of cancer, it is currently the only clear cause, and can be early prevention and radical treatment of cancer. Vaccination of HPV vaccine can not only effectively prevent the occurrence of cervical cancer and precancerous lesions, but also prevent the disease of other parts caused by HPV infection. However, China's vaccination situation is not optimistic, and vaccine hesitation is a major threat to the vaccination program. Although countries spend large amounts of money on vaccination campaigns yearly, the results show that these campaigns have little effect on increasing vaccination intentions and behavior. Therefore, it is of great practical significance and application value to take appropriate intervention measures to reduce vaccine hesitation and increase people's willingness to vaccinate. Based on this, this study will deeply explore the influencing factors of HPV vaccination intention, and on this basis, explore the persuasive effect of persuasive information constructed based on influencing factors, and explore the influence of personality on persuasive information, so as to provide scientific basis and reference for the design and delivery of targeted persuasive information for different groups, so as to strengthen the persuasive effect of information. So that social resources can be more effectively allocated and used.
Three sub-studies are designed in this paper. A semi-structured interview was conducted to identify the factors influencing HPV vaccination willingness. In study 2, exploratory factor analysis and confirmatory factor analysis were used to compile a questionnaire with good reliability and validity to assess the importance of factors influencing HPV vaccination intention, and at the same time, individuals' preferences for factors influencing vaccination willingness were measured. Study 3 verifies the feasibility of information persuasion based on influencing factors through two information persuasion experiments, and explores the influence of individual personality characteristics on the persuasion effect containing information of different influencing factors.
Study 1: Through the method of semi-structured interview, we explored the influencing factors of individual HPV vaccination willingness, and obtained 25 influencing factors such as vaccine safety, vaccine effectiveness, vaccination convenience, professionalism, conformity and data. At the same time, based on the TPB theory, five themes of influencing factors of HPV vaccination intention were initially explored: vaccine effectiveness and safety, perceived benefits, reference groups, reference information, and behavioral disorders.
Study 2: Through exploratory factor analysis, confirmatory factor analysis and reliability and validity test, a questionnaire containing 17 questions and 4 dimensions was constructed to evaluate the importance of factors influencing HPV vaccination intention. The four dimensions are: reference information (6 questions), reference population (5 questions), vaccine safety (3 questions), and behavioral disorders (3 questions). Among them, confirmatory factor analysis supported the 4-factor model (χ²/df<, RMR=0.059, RMSEA=0.054, GFI=0.928, TLI=0.914, IFI=0.929), showing good model fit. The Cronbach's α coefficient of the questionnaire was 0.846, and the retest reliability at a 4-week interval was 0.804. It shows that our questionnaire has good reliability and validity. In addition, individuals have different importance degrees for different influencing factors, and individuals with different personality characteristics have significant differences in evaluating the importance degrees of factors influencing HPV vaccination intention.
Study 3: The HPV vaccine and novel coronavirus vaccine were selected as representatives of the two types of vaccines, non-immunization program vaccine and immunization program vaccine, and two experimental studies of information persuasion were conducted. The research results verified the feasibility of information persuasion based on the influencing factors of vaccination willingness and found that information containing different influencing factors had significant differences in the persuasive effects of individuals. Further studies have confirmed that individual personality characteristics can affect the persuasive effect of information containing different influencing factors, and the influence shows different patterns in the information of different influencing factors.
In general, the conclusions of these studies are as follows:
(1) We obtained 25 influencing factors of HPV vaccination intention, including vaccine safety, vaccine effectiveness, vaccination convenience, professionalism, conformity, and data;
(2) A 17-item questionnaire with 4 dimensions (reference information, reference group, vaccine safety, and behavioral disorders) was formed to assess the importance of factors influencing HPV vaccination intention. The reliability and validity of the scale were good, and it could be used to evaluate the preference of the factors influencing the intention of HPV vaccination.
(3) It is feasible to compile information and conduct persuasion based on the influencing factors of vaccination intention, and information containing different influencing factors has significant differences in the persuasive effects of individuals;
(4) Individual personality characteristics will affect the persuasive effect of information containing different influencing factors, and such influence has different effects on information containing different influencing factors.
This study explored the factors that affect the intention to vaccinate, and on this basis studied the influence of the influencing factors on information persuasion. The results of this study will enrich the relevant research on the intention to vaccinate, and provide a more comprehensive and in-depth understanding. By comprehensively analyzing the interaction between individual psychological characteristics and information persuasion factors, we can reveal the role of more detailed individual differences in information acceptance and behavioral decision making. This will provide theoretical support for the formulation of targeted intervention strategies and personalized vaccine publicity, so that the publicity information can more accurately match the psychological characteristics and needs of different individuals. The results of this study will provide scientific basis for personalized vaccine publicity, which will help promote the promotion of vaccination intention and promote the improvement of public health. |
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